Publication Date:
2014-09-27
Description:
Article Several patients with metastatic prostate cancer have been shown to harbour tumours with markedly high mutation rates. Here, the authors characterise hypermutation in advanced prostate cancer samples and show that these samples have somatic mismatch repair gene mutations and microsatellite instability. Nature Communications doi: 10.1038/ncomms5988 Authors: Colin C. Pritchard, Colm Morrissey, Akash Kumar, Xiaotun Zhang, Christina Smith, Ilsa Coleman, Stephen J. Salipante, Jennifer Milbank, Ming Yu, William M. Grady, Jonathan F. Tait, Eva Corey, Robert L. Vessella, Tom Walsh, Jay Shendure, Peter S. Nelson
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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