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  • 1
    Publication Date: 2015-02-18
    Description: Nanocrystalline Tungsten Oxide (WO 3 ) samples having different average crystallite sizes 10nm, 11 nm, 22 nm and 26 nm were synthesized through controlled chemical precipitation method. The phase purity and average crystallite sizes were estimated from X-ray Diffraction (XRD) analysis. The vibrational characteristics of the samples were studied by Raman spectroscopy. The X-ray Photoelectron Spectroscopic (XPS) analysis of the samples revealed the presence of oxygen vacancies which was confirmed by the uv-visible (uv- vis) absorption and photoluminescence (PL) emission studies.
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 2
    Publication Date: 2015-02-18
    Description: Manganese oxides have generated considerable interest in recent years due to their electronic and magnetic properties with potential industrial applications. Among manganese oxides, Mn 3 O 4 is one of the stable oxides with normal spinel structure and it has variety of important applications. In the present work nanocrystalline Hausmannite, Mn 3 O 4 with phase purity and average crystallite size of 8 nm was synthesized through a novel sol-gel route at a temperature of 0-5°C. The samples were annealed at different temperatures to understand the thermal stability and the structural characterization was done using techniques such as X-ray powder diffraction (XRD), Transmission Electron Microscopy (TEM) and Fourier Transform Infrared Spectroscopy (FTIR). The UV visible absorption spectra of the samples show that there are two types of transitions corresponding to Mn 2+ ions and Mn 3+ ions. The dc electrical conductivity of th...
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 3
    Publication Date: 2001-05-12
    Description: T cell activation is dependent on both a primary signal delivered through the T cell receptor and a secondary costimulatory signal mediated by coreceptors. Although controversial, costimulation is thought to act through the specific redistribution and clustering of membrane and intracellular kinase-rich lipid raft microdomains at the contact site between T cells and antigen-presenting cells. This site has been termed the immunological synapse. Endogenous mediators of raft clustering in lymphocytes have not been identified, although they are essential for T cell activation. We now demonstrate that agrin, an aggregating protein crucial for formation of the neuromuscular junction, is also expressed in lymphocytes and is important in reorganization of membrane lipid microdomains and setting the threshold for T cell signaling. Our data show that agrin induces the aggregation of signaling proteins and the creation of signaling domains in both immune and nervous systems through a common lipid raft pathway.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Khan, A A -- Bose, C -- Yam, L S -- Soloski, M J -- Rupp, F -- R01AI20922/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2001 Jun 1;292(5522):1681-6. Epub 2001 May 10.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Outer Banks Neuroscience, Baltimore, MD 21218, USA. outerbanksneuro@yahoo.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11349136" target="_blank"〉PubMed〈/a〉
    Keywords: Agrin/genetics/metabolism/*physiology ; Alternative Splicing ; Animals ; Antigen-Presenting Cells/immunology/*physiology ; B-Lymphocytes/metabolism ; Glycosylation ; *Lymphocyte Activation ; Male ; Membrane Microdomains/*physiology ; Mice ; Neuromuscular Junction/physiology ; Neurons/physiology ; Rats ; Rats, Sprague-Dawley ; Receptor Aggregation ; Receptors, Antigen, T-Cell/physiology ; Receptors, Cholinergic/physiology ; Signal Transduction ; T-Lymphocyte Subsets/metabolism ; T-Lymphocytes/immunology/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2014-06-04
    Description: Transforming growth factor beta2 (TGFβ2) is a multifunctional protein which is expressed in several embryonic and adult organs. TGFB2 mutations can cause Loeys Dietz syndrome, and its dysregulation is involved in cardiovascular, skeletal, ocular and neuromuscular diseases, osteoarthritis, tissue fibrosis, and various forms of cancer. TGFβ2 is involved in cell growth, apoptosis, cell migration, cell differentiation, cell-matrix remodeling, epithelial-mesenchymal transition, and wound healing in a highly context-dependent and tissue-specific manner. Tgfb2 -/- mice die perinatally from congenital heart disease, precluding functional studies in adults. Here, we have generated mice harboring Tgfb2 β geo (knockout-first lacZ -tagged insertion) gene-trap allele and Tgfb2 flox conditional allele . Tgfb2 β geo/ β geo or Tgfb2 β geo/- mice died at perinatal stage from the same congenital heart defects as Tgfb2 -/- mice. β-galactosidase staining successfully detected Tgfb2 expression in the heterozygous Tgfb2 βgeo fetal tissue sections. Tgfb2 flox mice were produced by crossing the Tgfb2+/ β geo mice with the FLPeR mice. Tgfb2flox/- mice were viable. Tgfb2 conditional knockout (Tgfb2cko/-) fetuses were generated by crossing of Tgfb2flox/- mice with Tgfb2+/-;EIIaCre mice. Systemic Tgfb2cko/- embryos developed cardiac defects which resembled the Tgfb2 β geo/ β geo, Tgfb2 β geo/-, and Tgfb2 -/- fetuses. In conclusion, Tgfb2 β geo and Tgfb2 flox mice are novel mouse strains which will be useful for investigating the tissue specific expression and function of TGFβ2 in embryonic development, adult organs, and disease pathogenesis and cancer. © 2014 Wiley Periodicals, Inc.
    Topics: Biology , Medicine
    Published by Wiley
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  • 5
    Publication Date: 2014-07-23
    Description: Extracellular fatty acid incorporation into the phospholipids of Staphylococcus aureus occurs via fatty acid phosphorylation. We show that fatty acid kinase (Fak) is composed of two dissociable protein subunits encoded by separate genes. FakA provides the ATP binding domain and interacts with two distinct FakB proteins to produce acyl-phosphate. The...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 6
    Publication Date: 2015-10-30
    Description: Self-consistent N -body simulations of modified gravity models are a key ingredient to obtain rigorous constraints on deviations from general relativity using large-scale structure observations. This paper provides the first detailed comparison of the results of different N -body codes for the f ( R ), Dvali–Gabadadze–Porrati and Symmetron models, starting from the same initial conditions. We find that the fractional deviation of the matter power spectrum from cold dark matter agrees to better than 1 per cent up to k ~ 5–10 h Mpc –1 between the different codes. These codes are thus able to meet the stringent accuracy requirements of upcoming observational surveys. All codes are also in good agreement in their results for the velocity divergence power spectrum, halo abundances and halo profiles. We also test the quasi-static limit, which is employed in most modified gravity N -body codes, for the Symmetron model for which the most significant non-static effects among the models considered are expected. We conclude that this limit is a very good approximation for all of the observables considered here.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 7
    Publication Date: 2016-10-11
    Description: Difficult-to-cut materials have increasing demand in aerospace and automobile industries due to their high yield stress, high strength to weight ratio, high toughness, high wear resistance, high creep, high corrosion resistivity, ability to retain high strength at high temperature, etc. The machinability of these advanced materials, using conventional methods of machining is typical due to the high temperature and pressure at the cutting zone and tool and properties such as low thermal conductivity, high cutting forces and cutting temperatures makes the materials difficult to machine. Laser assisted machining (LAM) is a new and innovative technique for machining the difficult-to-cut materials. This paper deals with a review on the advances in lasers, tools and the mechanism of machining using LAM and their effects.
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 8
    Publication Date: 2016-10-12
    Description: Shape memory alloys (SMAs) are the special materials that have the ability to return to a predetermined shape when heated. When this alloy is in below transformation temperature it undergoes low yield strength and will deform easily into any new shape which it will retain, if this alloy is heated above its transformation temperature it changes its crystal lattice structure which returns to its real shape. SMAs are remarkably different from other materials are primarily due to shape memory effect (SME) and pseudoelasticity which are related with the specific way the phase transformation occurs, biocompatibility, high specific strength, high corrosion resistance, high wear resistance and high anti-fatigue property. SMA are used in many applications such as aerospace, medical, automobile, tubes, controllers for hot water valves in showers, petroleum industry, vibration dampers, ball bearings, sensors, actuators, miniature grippers, micro valves, pumps, landing gears, eye glass fram...
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
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  • 9
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 153 (1944), S. 23-23 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] DR. LONSDALE1 found a type of non-Laue reflexion from diamond which is different from the usual type of diffuse spots, and she mentions them as secondary extra reflexions. The spots of this type are, as distinguished from the primary type, extremely sharp for a special ...
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