ISSN:
1573-4935
Keywords:
collagen
;
cornea
;
synchrotron
;
bovine
;
X-ray diffraction
;
glycoprotein
;
GP 135
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract Treatment of bovine corneal stroma using SDS-containing extracting solutions removes a 135,000 MW glycoprotein from the main collagen framework of the tissue. Low-angle synchrotron X-ray diffraction patterns obtained from corneas extracted in this way indicate that the glycoprotein has been removed from the gap regions of the collagen fibrils and is thus an important structural component of the corneal stroma. The glycoprotein (GP 135) shares a number of properties with one of the subunits of type VI collagen, but tests have so far failed to establish their identity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01128974
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