ISSN:
1573-4927
Keywords:
acetylcholinesterase
;
gene duplication
;
Culex pipiens
;
insecticide resistance
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract InCulex pipiens mosquitoes, AChE1 encoded by the locusAce.1 is the target of organophosphorus and carbamate insecticides. In several resistant strains homozygous forAce.1 RR , insensitive AChE1 is exclusively found. An unusual situation occurs in two Caribbean resistant strains where each mosquito, at each generation, displays a mixture of sensitive and insensitive AChE1. These mosquitoes are not heterozygotes,Ace.1 RS , as preimaginal mortalities cannot account for the lethality of both homozygous classes. This situation is best explained by the existence of twoAce.1 loci, coding, respectively, a sensitive and an insensitive AChE1. Thus, we suggest that in the Caribbean a duplication of theAce.1 locus occurred before the appearance of insecticide resistance at one of the two copies.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00554410
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