ISSN:
1573-1111
Keywords:
18C6 crown ether
;
cyclogentiotetraose peracetate
;
alkali cations
;
complexation
;
stability constants
;
fast atom bombardment mass spectrometry
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Quantitative studies of the complexation of the macrocylic ligands, 18 crown 6 (18C6,1) and cyclogentiotetraose peracetate (CGD4Ac,2), with alkali cations, have been investigated by fast atom bombardment mass spectrometry (f.a.b.m.s.). Complexation curves of 18C6 with Na+, K+, Rb+ and Cs+ in glycerol, and of CGD4Ac with Cs+ in PEG 200, were obtained by plotting the complex peak intensity against the alkali cation concentration. From these curves we describe a method to calculate the stability constant for an alkali cation-macroyclic ligand complex. There is a good agreement between stability constants obtained either by f.a.b.m.s. or calorimetric techniques for 18C6-alkali cation complexes. These results suggest that the f.a.b. technique can be used to study complex formation and determine the stability constant.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01084713
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