ISSN:
0170-2041
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Terpenes and Terpene Derivatives, XIII1). - Synthesis of (±)-8,9-DehydroasterolideFrom the ketoester 2 the α,β-unsaturated ketone 9 is prepared via ketalization (→ 3), hydroboration (→ 4), oxidation (→ 6), Wittig reaction (→ 7), hydrolysis (→ 8a), and oxidative decarboxylation. 9 is a useful starting material for the synthesis of 8,9-dehydroasterolide (1) via epoxidation (→ 10), PO olefination (→ 11, hydrolysis (→ 12), and dehydratization.
Notes:
Aus dem Ketoester 2 wird durch Ketalisierung (→ 3), Hydroborierung (→ 4), Oxidation (→ 6), Wittig-Reaktion (→ 7), Hydrolyse (→ 8a) und oxidative Decarboxylierung das α,β-ungesättigte Keton 9 dargestellt. Daraus wird durch Epoxidierung (→ 10), PO-Olefinierung (→ 11), Hydrolyse (→ 12) und Dehydratisierung 8,9-Dehydroasterolid (1) erhalten.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.198219820108
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