Publication Date:
2014-04-24
Description:
Key Points PSTPIP1 regulates the transition from podosomes to filopodia in macrophages by modulating WASP activity. The novel PSTPIP1-R405C mutant induces filopodia formation, increases matrix degradation, and is associated with severe pyoderma gangrenosum.
Print ISSN:
0006-4971
Electronic ISSN:
1528-0020
Topics:
Biology
,
Medicine
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