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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Evolution (Biology). ; Sexual selection. ; Molecular Evolution. ; Anthropology. ; Evolutionary Theory. ; Sexual Selection. ; Molecular Evolution. ; Anthropology.
    Description / Table of Contents: Chapter 1 -- Light would be thrown: human evolution one hundred and fifty years after Darwin -- Chapter 2. The historical background to Darwin’s Descent of Man -- Chapter 3.Ways of seeing the world: Darwin and the first Victorian generation -- Chapter 4. The problem of design in the Darwinian proposal: A historical overview -- Chapter 5. Darwin under suspicion: The representation of Darwinism in the newspaper ABC (1909-1982) -- Chapter 6.The Descent of Man: Darwin and psychology -- Chapter 7.Human evolution. The linguistic evidence -- Chapter 8.Human evolution in Eurasia: The fossils that Darwin did not know -- Chapter 9. Human evolution: The genomic evidence -- Chapter 10.The adaptations that made us human: Morphology -- Chapter 11.The adaptations that have made us human: The genome -- Chapter 12. How do we humans evolve? -- Chapter 13. Art as a human element -- Chapter 14.Sexual selection: Following Darwin's legacy -- Chapter 15. Genetic and cultural evolution of mate choice -- Chapter 16.How past shapes future: The biological future of humankind.
    Abstract: This book presents a series of perspectives showing the current knowledge about human evolution. On the occasion of the 150th anniversary of Darwin's book, The Descent of Man, and Selection in Relation to Sex, in which he explicitly addresses the natural origin of the human species, this collective work reviews current and diverse aspects of human evolution: from psychology, linguistics, genomics, paleontology, artistic expression or sexual selection. It also offers a historical, social and ideological context of what is often considered to be Darwin's second great work after The Origin of Species. Although current research is concentrated largely on fossils and genomes, this book also deals with the main points Darwin centered his attention on; comparative morphology and psychology, and sexual selection. It also covers other new aspects, such as the origin of art, social structure and social learning. With contributions from leading experts in their respective fields, the book guides readers to the study of the social context of Darwin and his time, and the state of the art of studies on human evolution and sexual selection, considering all aspects that Darwin examined, including those that emerged later and now are important disciplines in our understanding of our own evolution. The English translation of parts of this book from its Spanish original manuscript was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content.
    Type of Medium: Online Resource
    Pages: VIII, 217 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811932465
    Series Statement: Evolutionary Studies,
    DDC: 576.801
    Language: English
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  • 2
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Binary polymorphisms associated with the non-recombining region of the human Y chromosome (NRY) preserve the paternal genetic legacy of our species that has persisted to the present, permitting inference of human evolution, population affinity and demographic history. We used denaturing ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature genetics 8 (1994), S. 216-218 
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] IN REPLY — The use of variation at microsatellite markers to trace the evolution of a disease mutation has no precedent in molecular population genetics. Thus, we are dealing with a new situation which may be difficult to understand and which will benefit from further experience with other ...
    Type of Medium: Electronic Resource
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  • 4
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    Baltimore : Periodicals Archive Online (PAO)
    Human Biology. 66:5 (1994:Oct.) 823 
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  • 5
    ISSN: 1432-1432
    Keywords: Key words: Y chromosome — STR — Microsatellite — Basques — Catalans — Haplotype
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. Eight human short tandem repeat polymorphisms (STRs) also known as microsatellites—DYS19, DYS388, DYS390, DYS391, DYS392, DYS393, DYS389I, and DYS389II, mapping in the Y chromosome—were analyzed in two Iberian samples (Basques and Catalans). Allele frequency distributions showed significant differences only for DYS392. Fst and gene diversity index (D) were estimated for the Y STRs. The values obtained are comparable to those of autosomal STR if corrections for the smaller effective population size on the Y chromosome are taken into account. This suggests that Y-chromosome microsatellites might be as useful as their autosomal counterparts to both human population genetics and forensics. Our results also reinforce the hypothesis that selective sweeps in the Y chromosome in recent times are unlikely. Haplotypes combining five of the loci were constructed for 71 individuals, showing 29 different haplotypes. A haplotype tree was constructed, from which an estimate of 7,000 to 60,000 years for the age of the Y-chromosome variation in Iberia was derived, in accordance with previous estimates obtained with mtDNA sequences and nuclear markers.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] In a study of human diversity at a highly variable locus, we have mapped the internal structures of tandem–repetitive alleles from different populations at the minisatellite MS205 (D76S309).The results give an unusually detailed view of the different allelic structures represented on modern ...
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Abnormalities of the serotonergic system have classically been associated with the origin of affective disorders through the biochemical action of therapeutic agents and their role in affective and perceptual states. In the present study, we hypothesized that genetic variation in the 5-hydroxytryptamine (serotonin) type 2A (5-HT2A ) receptor gene (HTR2A) might have an effect on the aetiology of bipolar affective disorder. Four different polymorphisms in the HTR2A gene were studied in 88 patients with bipolar affective disorder and 113 healthy controls, all of Spanish origin. No significant association was observed between any of the four polymorphisms at the HTR2A locus, whether tested individually or as haplotypes, and bipolar affective disorder. The lack of association suggests that HTR2A is not a major risk factor for bipolar affective disorder.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The serotonin transporter (SERT) gene is a particularly interesting candidate for genetic involvement in affective disorders owing to its role in both the regulation of serotonergic neurotransmission and the mechanism of action of many antidepressant drugs. In this study, variability in the SERT gene was analyzed for the first time in a sample of patients with major depression with melancholia (MDDM) in the context of a genetic association study. Two different polymorphisms of the SERT gene (17q11.1–17q12) were analyzed: a variable number of tandem repeats (VNTR) polymorphism in intron 2, and a deletion/insertion polymorphism (5-HTTLPR) in the promoter region of the gene, the short variant of which (allele 484) reduces the transcriptional efficiency of the SERT gene. Our sample consisted of 74 unrelated subjects who strictly met DSM-IV criteria for MDDM and 84 healthy controls, all of Spanish origin. The analysis of haplotype distribution for both polymorphisms showed significant differences between cases and controls (log-likelihood ratio χ2=11.15, df=4, P=0.025). Moreover, when the frequencies of the 484-STin2.10 haplotype were considered in comparison with any other haplotype combination, a significant increase in this haplotype was found in patients with MDDM [z=2.53 (95% CI, 1.21–5.34), P=0.007]. According to these results, variability in the SERT gene has a small effect on liability to MDDM. Our findings are compatible with an additive effect of both the 484 low-activity allele and a mutation elsewhere within the transporter gene or a susceptibility locus nearby in linkage disequilibrium with the VNTR marker.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. An analysis of 11 Alu insertion polymorphisms (ACE, TPA25, PV92, APO, FXIIIB, D1, A25, B65, HS2.43, HS3.23, and HS4.65) has been performed in several NW African (Northern, Western, and Southeastern Moroccans; Saharawi; Algerians; Tunisians) and Iberian (Basques, Catalans, and Andalusians) populations. Genetic distances and principal component analyses show a clear differentiation of NW African and Iberian groups of samples, suggesting a strong genetic barrier matching the geographical Mediterranean Sea barrier. The restriction to gene flow may be attributed to the navigational hazards across the Straits, but cultural factors must also have played a role. Some degree of gene flow from sub-Saharan Africa can be detected in the southern part of North Africa and in Saharawi and Southeastern Moroccans, as a result of a continuous gene flow across the Sahara desert that has created a south-north cline of sub-Saharan Africa influence in North Africa. Iberian samples show a substantial degree of homogeneity and fall within the cluster of European-based genetic diversity.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The geographical distribution of 49 mtDNA sequences from 22 localities in Southern Tuscany, Italy, was studied by molecular analysis of variance, by a new spatial autocorrelation statistic specifically designed for sequence data and by reconstructing genealogies of haplotypes. All these methods indicated a high homogeneity of populations. Nevertheless, genetic variability showed significant departure from equilibrium expectations, in agreement with the predicted effects of a population expansion. We suggest that a past population expansion that was probably associated with a migrational wave and with local gene flow between localities prevented spatial structuring in Southern Tuscany.
    Type of Medium: Electronic Resource
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