ISSN:
1432-041X
Keywords:
Key words Spinal cord
;
Regeneration
;
Amphibian urodeles
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract After tail amputation in urodele amphibians, dramatic changes appear in the spinal cord rostral to the amputation level. Transection induces a proliferation response in cells lining the ependymal canal, giving rise to an ependymal tube in which neurogenesis occurs. Using the thymidine analog bromodeoxyuridine (BrdU) in short- and long-term labeling of cells undergoing DNA synthesis (S phase of the cell cycle), specific cell markers, and cell cultures, we show that neurons derive from the proliferative ependymal layer of the ependymal tube.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004270050265
Permalink