ISSN:
1573-8353
Keywords:
tetrahydropyridines
;
tetrahydropyridin-2-ones
;
dihydroxylation
;
lactamization
;
potassium permanganate oxidation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Oxidation of 4-phenyl-, 4-(4-pyridyl)-, and 4-phenethenyl-1,2,3,6-tetrahydropyridines with potassium permanganate can stop at the stage of the introduction of an oxo group into the allyl C(2) position of the piperideine fragment. In contrast to their precursors, 4-aryltetrahydropyridin-2-ones obtained in this way can be converted to 3,4-dihydroxy-2-oxopiperidines under Wagner reaction conditions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1017570313032
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