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  • 1
    Electronic Resource
    Electronic Resource
    Insulin, Neuropeptide Y, and Food Intake (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 692 (1993), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1993.tb26206.x
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  • 2
    Electronic Resource
    Electronic Resource
    Central nervous system control of food intake (2000)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 404 (2000), S. 661-671 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] New information regarding neuronal circuits that control food intake and their hormonal regulation has extended our understanding of energy homeostasis, the process whereby energy intake is matched to energy expenditure over time. The profound obesity that results in rodents (and in the rare ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/35007534
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  • 3
    Electronic Resource
    Electronic Resource
    Melanocortin receptors in leptin effects (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 349-349 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Leptin acts on the central nervous system to cause a reduction in food intake and body weight,. The melanocortin system in the brain is also implicated in energy homeostasis, with agonists of the melanocortin-4 (MC4) receptor reducing food intake and targeted mutation of the MC4 receptor ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/37016
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  • 4
    Electronic Resource
    Electronic Resource
    The fine structure of neuroglia in the central nervous system of nereid polychaetes (1971)
    Springer
    Cell & tissue research 119 (1971), S. 295-308 
    Details
    ISSN: 1432-0878
    Keywords: Fine structure ; Neuroglia ; Nervous system ; Polychaetes ; Cell junctions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The principal supportive elements of the nereid central nervous system are non-neuronal cells that are referred to as supportive glia. Supportive glial cells form a conspicuous cortex in the nerve cord. The inner region of this cortex consists of closely packed processes and cell bodies of fibrous supportive glial cells that are arranged in concentric layers around the perimeter of the neuropile. The fibrous appearance of the glial cells results from dense bundles of cytoplasmic filaments. Many fibrous glial processes penetrate the neuropile and ramify among the neuronal elements. Larger, irregularly shaped cells are the chief supportive glial elements of the peripheral region of the cortex where they line the stromal sheath (neural lamella) and invest the neuronal perikarya with extensive concentric systems of lamellate processes. These glial cells usually possess a relatively undifferentiated cytoplasm with scattered glycogen granules, but occasionally have a well developed Golgi apparatus, endoplasmic reticulum and densely packed particulate glycogen. The supportive glia exhibits numerous desmosomes as well as 5-layered (“tight”) and 7-layered (“gap”) junctions. Interspersed among the supportive glial cells are non-neuronal cells referred to as granulocytes. These cells have abundant large, granular inclusions, electron lucent vesicles, plasmalemmal infoldings and microtubules. The granulocytes may be derived from undifferentiated glial cells or may represent coelomocytes that have invaded the nervous tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00431288
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  • 5
    Electronic Resource
    Electronic Resource
    Electron microscopic study on the gill bars of amphioxus (Brachiostoma californiense) with special reference to Neurociliary control (1976)
    Springer
    Cell & tissue research 166 (1976), S. 167-178 
    Details
    ISSN: 1432-0878
    Keywords: Gill bars ; Fine structure ; Neurociliary control ; Neurosecretion ; Cephalochordata
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Both primary and secondary (tongue) bars of the pharyngeal gill basket are covered by epithelial cells that are continuous with the cells that line the atrium. Anterior and posterior faces of the gill bars are covered with lateral ciliated cells, which possess a single cilium, ringed by microvilli, and an elaborate basal mitochondria-rootlet apparatus. Pharyngeal faces of the gill bars are covered with ciliated pharyngeal cells, atrial faces by mucus secreting atrial cells. The surface epithelium rests on a stromal septum, a flattened tube of basal lamina which dilates to form the visceral blood vessel (along the pharyngeal face) and skeletal blood vessel (along the atrial face). This basal lamina surrounds paired skeletal rods which run through the longitudinal axis of the gill bars near the atrial face. Between the skeletal rods and atrial cells of primary gill bars is a coelomic channel lined by epithelioid coelomic cells. Neuronal processes, some with neurosecretory granules, are located among the bases of the atrial cells. Some axons may contact lateral ciliated cells where the latter meet atrial cells, but synaptoid endings have not been found here or elsewhere in the gill bars. Nervous tissue has not been identified among lateral ciliated cells even though ciliary activity of these cells is supposedly regulated by atrial nervous tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00227038
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  • 6
    Electronic Resource
    Electronic Resource
    Further observations on the fine structure and development of the infracerebral complex (“infracerebral gland”) of Nereis limnicola (Annelida, Polychaeta) (1974)
    Springer
    Cell & tissue research 154 (1974), S. 519-531 
    Details
    ISSN: 1432-0878
    Keywords: Infracerebral complex ; Polychaeta, Nereidae ; Neurosecretion ; Fine structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The infracerebral complex consists of: (a) two types of ependymoid infracerebral cells located on the ventral surface of the brain, adjacent to a coelomic sinus and blood vessels; (b) a noncellular stroma, the neural lamella, which separates the infracerebral cells from cerebral nervous tissue; (c) two types of cerebral neurosecretory endings (one with many mitochondria) which abut on the neural lamella opposite from the infracerebral cells. The infracerebral a cells become columnar and develop abundant apical caveolae and Golgi elements in older worms. The infracerebral b cells, filled with electron opaque granules, resemble neurosecretory cells; their axon-like processes contain microtubules and make synaptoid contacts with the neural lamella. Both cell types are present in young worms of about 10 segments but the b cells, relatively abundant in younger worms, are outnumbered by a cells in mature individuals. However, during reproductive development neither a nor b cells display any structural changes which would indicate that they represent glandular tissue. Basal processes originating both from a and b cells form entanglements which become progressively more intricate during maturation. Neurosecretory endings are present in 10-segment worms and become very numerous in mature worms but at no time do they penetrate the neural lamella and contact the infracerebral cells. It is unlikely that the infracerebral cells per se constitute a gland but they are strategically located to influence the release of hormones from neurosecretory endings.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219671
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  • 7
    Electronic Resource
    Electronic Resource
    The fine structure of polychaete septate junctions (1976)
    Springer
    Cell & tissue research 174 (1976), S. 55-67 
    Details
    ISSN: 1432-0878
    Keywords: Septate junctions ; Polychaeta ; Fine structure ; Cell junctions ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Epidermal septate junctions of Nereis sp. and Cirriformia sp. fixed with OsO4 or glutaraldehyde/OsO4 display variable structure in electron micrographs. In transverse section the septa are often indistinct and obscured by opaque material that fills the junctional cleft. Septa (spaced at 180–280 Å) are more clearly defined in slightly oblique transverse section; they exhibit an electron lucent center and appear to be linked by arms. En face views of the junction show a honeycomb pattern. Cytoplasmic faces of junctional membranes are backed with plaques opposite the septa. Lanthanum used as a tracer delineates junctional structure in negative contrast. In transverse section a chain-like lattice is present in the junctional cleft. En face views show parallel rows of pleated elements often linked by arms into honeycomb arrays. Oblique sections demonstrate that these pleated elements are continuous with the chain-like lattice seen in transverse sections. Lanthanum does not pass entirely through the junction. Lanthanum reveals that the septa have a very intricate substructure, but it is difficult to visualize the architecture that could generate the various images presented by these junctions when seen in different orientations. However, it is clear that these junctions possess some features that are diagnostic of several supposedly different types of septate junctions in invertebrates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00222150
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  • 8
    Electronic Resource
    Electronic Resource
    A possible neuroendocrine system in polynoid polychaetes (1971)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 133 (1971), S. 93-103 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Within the supraesophageal ganglion of polynoids is a vertical fiber tract which has the appearance of a “Y” in transverse sections of the brain, and contains the axons of many neurosecretory cells. The granule-filled terminals of these neurosecretory fibers are found at the base of the tract where they are in contact with the inner surface of the sheath covering the ventral surface of the brain. This sheath separates these neurosecretory endings from an underlying pericapsular epithelium which is thicker in this region. Beneath this pericapsular epithelium is a coelomic sinus. The dorsal blood vessel is located within this sinus and is “innervated” by a pair of fiber bundles that pass out of the brain at the base of the vertical fiber tract. The outer surface of the vessel is covered by epithelioid cells which contact these fiber bundles and the thickened pericapsular epithelium, and sometimes contain granular cytoplasmic inclusions. The lumen of the vessel is continuous with the lumina of a pair of cellular, thickwalled structures of unknown function which are attached to the ventro-lateral margins of the brain. The relationship between neurosecretory endings, enlarged pericapsular cells, coelomic sinus and blood vessel provides morphological evidence for the hypothesis that these structures are elements of a neuroendocrine system, similar in some respects to the brain-infracerebral gland complex of nereid and nephtyid polychaetes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051330105
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  • 9
    Electronic Resource
    Electronic Resource
    The infracerebral gland  -  a possible neuroendocrine complex in Nereis (1968)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 124 (1968), S. 187-215 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The infracerebral gland of Nereis consists of an epithelium covering the ventral surface of the posterior region of the brain. The thickness of the epithelium varies greatly in different species, and it appears especially well developed in Nereis limnicola. Cells of the most numerous type are in direct contact with the base of the brain. Their apical surfaces bound a coelomic sinus, below which is a blood plexus. Other cells are fuchsinophilic and contain many inclusions resembling elementary neurosecretory granules. A third type is rare and resembles glial elements. A number of nerve tracts run from the neuropil to the base of the brain in the region of the gland. Where they impinge upon the capsule they form swellings containing elementary granules and small vesicles. Some axons do not end on the capsule but pass through the capsule and then ramify among the cells of the gland. The swollen endings of other fibers, probably nervous in character, are packed with mitochondria and are scattered over the inner surface of the capsule in the region of the gland. The features described are suggestive of a neuroendocrine complex, and the relation between the brain and the infracerebral gland is in need of experimental analysis in view of the important endocrine functions presently ascribed to the brain in nereids.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051240206
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  • 10
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    The fine structure of neuroglia in the central nervous system of nereid polychaetes (1971)
    Springer
    Details
    Publication Date: 1971-01-01
    Print ISSN: 0302-766X
    Electronic ISSN: 1432-0878
    Topics: Biology , Medicine
    Published by Springer
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