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  • 1
    Electronic Resource
    Electronic Resource
    Significance of the Porosity and Physical Chemistry of Calcium Phosphate Ceramics (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 523 (1988), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1988.tb38521.x
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  • 2
    Electronic Resource
    Electronic Resource
    Ultraweak photon emission in germinating seeds: A signal of biological order (1991)
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 6 (1991), S. 227-230 
    Details
    ISSN: 0884-3996
    Keywords: Ultraweak photon emission ; germinating gram seeds ; biological order ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Photon emission from germinating gram seeds at various stages of growth exhibits a definite pattern. The pattern of emission changes when a seed is disrupted by physical processes, e. g. mechanical crushing, cooling or heating. The disrupted seeds do not grow. The change in the biological order responsible for seed growth and the observed changes in the pattern of photo emission suggest a link between the macroscopic spatio-temporal organization and metabolic processes.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bio.1170060403
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  • 3
    Electronic Resource
    Electronic Resource
    Light-induced biophotonic emission from plant tissues (1992)
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 7 (1992), S. 177-184 
    Details
    ISSN: 0884-3996
    Keywords: Biophotons ; light-induced structure ; lichen ; photosynthetic unit ; inhibitors ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: The emission of biophotons in the visible range, following a delay time of 2-200 seconds after exposure to light, has been measured in germinating seeds, roots, flowers, leaves, and cells. It was found that the biophotonic signals are reproducible and light-induced. The observed signals from germinating seeds of Phaseolus aures and decaying leaves of Eucalyptus are presented to show that the signals have characteristic kinetics and intensity. The kinetics of the signal was found to be independent of the stage of growth or decay, though its intensity varied with biological factors. The kinetics in the first minute is characterized by a single exponential decay term while that in the region t ≤ 200 s is characterized by two exponentials. The variation in the intensity of the signal with mass, state of hydration, and growth, and the effect of inhibitors in various systems (e.g. leaves, lichen, Chlorella) are reported.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bio.1170070304
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  • 4
    Electronic Resource
    Electronic Resource
    An evaluation of inert and resorbale ceramics for future clinical orthopedic applicationsResearch Supported by the University of Dayton, Dayton, Ohio. (1971)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 5 (1971), S. 25-51 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The compatibility of implanted ceramic materials with autogenous bone, and the subsequently noted influence of the ceramic on the rate of new bone formation, were investigated to evaluate such materials for use in orthopedic implants. Three ceramic materials, aluminium oxide (Al2O3), zirconium oxide (ZrO2), and calcium aluminate (yCaO · xAl2O3) were tested. These were placed in the femurs of rhesus monkeys for periods of 50, 100, and 350 days. Definite compatability between the autogenous bone and the materials was exhibited for the implant time periods evaluated. No toxicogenic activity was noted in any of the biochemical, biomedical, and ceramographic evolutions. An added benefit resulted from the calcium aluminate composition, which was fabricated as a two-phase oxide material to make it slightly soluble in the body fluids. In the 50- and 100- day implants, the bone penetrated the ceramic for distances up to 100 μ while the ceramic dissolved and the pores enlarged. In addition, the mineralization in the area of the calcium aluminate was greater than that found around the other ceramics. Radiographs over the entire 350-day implant period confirmed the increased callus formation around all of the materials with no signs of rejection evident in the surrounding osseous or soft tissues. After 350 days the entire pore area of the calcium aluminate ceramic was infiltrated with a columnar substance which on the basis of scanning electron microscope procedures was considered to be mineralized osteoid.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820050104
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  • 5
    Electronic Resource
    Electronic Resource
    Immunogenicity of glutaraldehyde-treated bovine pericardial tissue xenografts in rabbits (1985)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 19 (1985), S. 1-12 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Xenograft valves of glutaraldehyde-treated bovine pericardial tissue have been claimed to be an excellent choice for the replacement of malfunctioning human heart valves. These valves exhibit low thrombogenicity, hemodynamic function, and transvalvular gradients superior to their mechanical and tissue counterparts. However, there are differences of opinion concerning the immunogenic properties of these valvular devices. This study was conducted to evaluate the immune reactivity of such implants. Data obtained indicated that whole xenograft sections of both untreated and treated valvular tissue remain immunogenic following initial and secondary subcutaneous implantations in rabbits. Homologous and cross-reacting antibodies were detected by means of indirect hemagglutination test 30 days after initial implantation of the grafts. Presence of cellular immune response as judged by skin reaction and leukocyte migration inhibition tests indicated that glutaraldehyde treatment of tissues does not destroy cellular immunity. Data obtained also suggest that chemical modification of such implants by glutaraldehyde probably alters, but does not abolish some antigenic determinant sites on the tissue surface. Glutaraldehyde treatment of bovine pericardial tissue does not render the tissue immunologically inert.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820190103
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  • 6
    Electronic Resource
    Electronic Resource
    Ceramic systems for long-term delivery of chemicals and biologicals (1988)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 22 (1988), S. 1245-1266 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Evaluation of devices, drugs, and drug delivery systems have been investigated by both in vitro and in vivo procedures. Ceramic drug delivery systems can be used to evaluate chemicals and biologicals by both in vitro and in vivo procedures. The system can also reduce handling of the animals and facilitate long-term evaluations before conducting clinical trials. To date, ceramic systems have been used to deliver aldosterone, androstanedione, beta-lactoglobulin, bovine serum albumin, chymotrypsin, danazol, difluoromeythylornithine, dihydrotestosterone, estradiol, gamma globulin, gonadotrophic releasing hormone, gossypol, growth hormone, insulin, methylene blue, pepsin, progesterone, and testosterone. The data obtained suggest that ceramic delivery systems can be used in the near future to treat diseases requiring long-term chronic drug therapy as well as disorders caused by deficiency of certain hormones.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820221212
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  • 7
    Electronic Resource
    Electronic Resource
    Analysis of the biocompatibility of ALCAP ceramics in rat femurs (1988)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 22 (1988), S. 1101-1126 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Ceramics composed of aluminum, calcium, and phosphorus oxides (ALCAP) were tested for compatibility as bone replacement biomaterials. Implantation of ALCAP ceramics in rat femurs had no deleterious effect on body weights, organ/body weight ratios, muscle, bone, blood, and kidney function. Aluminum resorbed from ALCAP ceramic bone implants was excreted in the urine and was not deposited in adjacent muscle. Plasma levels of aluminum were not elevated in rats implanted with ALCAP ceramics. Alkaline phosphatase activity of excised implant sites indicated greater bone formation in ALCAP ceramic implants than in bone autografts. Radiographs and implant histology demonstrated excellent bone association with implants and ingrowth of new bone into ALCAP ceramic implants. ALCAP ceramics are biocompatible and suitable for reconstruction of bone.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820221205
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  • 8
    Electronic Resource
    Electronic Resource
    Resorbable ceramic implantsResearch Supported by the University of Dayton, Dayton, Ohio. (1971)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 5 (1971), S. 91-115 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The purpose of the investigation was to show the ability of two calcium aluminate ceramic compositions to act as suitable implants for partial replacements of long bones. It was anticipated from previous studies that the ceramic would be well tolerated by the autogenous bone and surrounding soft tissue while the ceramic was slowly dissolving in the body fluids, allowing new osseous tissue to penetrate the resulting pore structure. It was expected that after a period of time the ceramic would no longer exist as a separate entity but would be completely infiltrated with mineralized osseous tissue and ultimately be completely replaced by bone. Two ceramic implants were prepared by slightly different techniques and CaO to Al2O3 ratios. The result was a polyphase ceramic and a nearly single phase ceramic. The polyphase material, after implantation in the test subject for 32 weeks, was completely impregnated with connective tissue while undergoing considerable alteration in microstructure. The single-phase material was not altered significantly in any way. This implant could not be fully evaluated for its ability to allow for osseous tissue formation on its surface, or within its open pore structure, due to slight variations in the original fixation of the implant and resulting attempts to correct the problems.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820050610
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  • 9
    Electronic Resource
    Electronic Resource
    Structure of some arylazophenols and arylazonaphthols in the solid state: A resonance Raman study (1995)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 26 (1995), S. 217-222 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: A resonance Raman study of (2-hydroxy-5-metheylphenylazo)benzene and (2-hydroxynaphthylazo)benzene and their derivatives is presented. The characteristic modes in the azo and hydrazone forms are identified. Structures for both types of compounds in the solid state are proposed. It is shown that hydroxy substitution at the ortho position forms a hydrogen bond with the nitrogen atom of the azo group in arylazophenols. The effect of ring substitution on the characteristic modes is also discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250260303
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  • 10
    Electronic Resource
    Electronic Resource
    Structural characterization of some quinolin-8-ol-containing azo dyes in solid and solution state as probed by resonance Raman, fourier transform IR and electronic spectroscopic techniques (1995)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 26 (1995), S. 351-361 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Some 5-(aryl)azoquinolin-8-ol derivatives were studied by resonance Raman, Fourier transform IR and electronic spectroscopic techniques. Analysis of vibrational and electronic spectra was used to determine the azo and hydrazone forms in both the solid and solution states. In the solid state, the compounds remain dominantly in one form and the characteristic bands due to each resonating form were identified. Various structural motifs for protonated, neutral and deprotonated states were proposed based on pH-dependent studies. The effect of H-bonding in stabilizing a particular type of structure is also discussed.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250260506
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