ISSN:
1432-0983
Keywords:
Aspergillus nidulans
;
p-fluoro-phenylalanine resistance
;
Dominant lethal mutations
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary An unexpectedly large number of p-fluorophenylalanine (FPA)-resistant mutants have been recovered after UV-irradiation of wild type diploid conidia of Aspergillus nidulans. At least five different classes of mutants, possibly corresponding to five different loci, have been identified. Two of them may be the dominant loci which have already been described but the others (a minimum of three loci) are completely different. Mutations in these loci confer high level FPA resistance in the heterozygous diploids, being lethal in the haploids; one mutation has been preliminarily mapped to chromosome I and another to chromosome III.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00313081
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