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  • 1
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    Fiftieth Anniversary Symposia : Mineralogy and Petrology of the Upper Mantle - Sulfides - Mineralogy and Geochemistry of Non-Marine Evaporites (1970)
    Chantilly, VA : Mineralogical Society of America
    Details
    Description / Table of Contents: The Mineralogical Society of America on November 8 and 9, 1969, celebrated the fiftieth anniversary of its founding in Atlantic City, New Jersey. The celebration included the presentation of three special symposia, with Harry H. Hess of Princeton University as chairman of the symposia committee. He personally organized the sessions for a symposium on the Mineralogy and Petrology of the Upper Mantle. A symposium on Sulfides was organized by Gunnar Kullerud of the Geophysical Laboratory, and a symposium on the Mineralogy and Geochemistry of Non-Marine Evaporites was organized by Blair F. Jones of the U. S. Geological Survey.
    Pages: Online-Ressource (VIII, 319 Seiten)
    URL: http://www.minsocam.org/msa/OpenAccess_Publications/MSA_Special_Papers/MSA_SP_3/MSA_SP_3.html
    Language: English
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    E-BOOK
  • 2
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    Toward a more scientific science (2018)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2018-09-21
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    The increasing dominance of teams in production of knowledge (2007)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2007-04-14
    Description: We have used 19.9 million papers over 5 decades and 2.1 million patents to demonstrate that teams increasingly dominate solo authors in the production of knowledge. Research is increasingly done in teams across nearly all fields. Teams typically produce more frequently cited research than individuals do, and this advantage has been increasing over time. Teams now also produce the exceptionally high-impact research, even where that distinction was once the domain of solo authors. These results are detailed for sciences and engineering, social sciences, arts and humanities, and patents, suggesting that the process of knowledge creation has fundamentally changed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wuchty, Stefan -- Jones, Benjamin F -- Uzzi, Brian -- New York, N.Y. -- Science. 2007 May 18;316(5827):1036-9. Epub 2007 Apr 12.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Northwestern Institute on Complexity (NICO), Northwestern University, Evanston, IL 60208, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17431139" target="_blank"〉PubMed〈/a〉
    Keywords: *Authorship ; Bibliometrics ; Biomedical Research/statistics & numerical data/trends ; Databases as Topic/statistics & numerical data ; Engineering ; Humanities ; *Knowledge ; *Patents as Topic ; Publishing/statistics & numerical data/*trends ; Research/statistics & numerical data/*trends ; Sociology ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Multi-university research teams: shifting impact, geography, and stratification in science (2008)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2008-10-11
    Description: This paper demonstrates that teamwork in science increasingly spans university boundaries, a dramatic shift in knowledge production that generalizes across virtually all fields of science, engineering, and social science. Moreover, elite universities play a dominant role in this shift. By examining 4.2 million papers published over three decades, we found that multi-university collaborations (i) are the fastest growing type of authorship structure, (ii) produce the highest-impact papers when they include a top-tier university, and (iii) are increasingly stratified by in-group university rank. Despite the rising frequency of research that crosses university boundaries, the intensification of social stratification in multi-university collaborations suggests a concentration of the production of scientific knowledge in fewer rather than more centers of high-impact science.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jones, Benjamin F -- Wuchty, Stefan -- Uzzi, Brian -- New York, N.Y. -- Science. 2008 Nov 21;322(5905):1259-62. doi: 10.1126/science.1158357. Epub 2008 Oct 9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Kellogg School of Management, Northwestern University, Evanston, IL 60208, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18845711" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli (2016)
    Oxford University Press
    Details
    Publication Date: 2016-05-20
    Description: Robust gene circuit construction requires use of promoters exhibiting low crosstalk. Orthogonal promoters have been engineered utilizing an assortment of natural and synthetic transcription factors, but design of large orthogonal promoter-repressor sets is complicated, labor-intensive, and often results in unanticipated crosstalk. The specificity and ease of targeting the RNA-guided DNA-binding protein dCas9 to any 20 bp user-defined DNA sequence makes it a promising candidate for orthogonal promoter regulation. Here, we rapidly construct orthogonal variants of the classic T7-lac promoter using site-directed mutagenesis, generating a panel of inducible hybrid promoters regulated by both LacI and dCas9. Remarkably, orthogonality is mediated by only two to three nucleotide mismatches in a narrow window of the RNA:DNA hybrid, neighboring the protospacer adjacent motif. We demonstrate that, contrary to many reports, one PAM-proximal mismatch is insufficient to abolish dCas9-mediated repression, and we show for the first time that mismatch tolerance is a function of target copy number. Finally, these promoters were incorporated into the branched violacein biosynthetic pathway as dCas9-dependent switches capable of throttling and selectively redirecting carbon flux in Escherichia coli . We anticipate this strategy is relevant for any promoter and will be adopted for many applications at the interface of synthetic biology and metabolic engineering.
    Keywords: Synthetic Biology and Assembly Cloning, Targeted gene modification
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 6
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    Resource scarcity drives lethal aggression [Anthropology] (2016)
    National Academy of Sciences
    Details
    Publication Date: 2016-10-26
    Description: The origin of human violence and warfare is controversial, and some scholars contend that intergroup conflict was rare until the emergence of sedentary foraging and complex sociopolitical organization, whereas others assert that violence was common and of considerable antiquity among small-scale societies. Here we consider two alternative explanations for the...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 7
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    Explaining California's prehistoric migrations [Anthropology] (2013)
    National Academy of Sciences
    Details
    Publication Date: 2013-09-04
    Description: Global patterns of ethnolinguistic diversity vary tremendously. Some regions show very little variation even across vast expanses, whereas others exhibit dense mosaics of different languages spoken alongside one another. Compared with the rest of Native North America, prehistoric California exemplified the latter. Decades of linguistic, genetic, and archaeological research have...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 8
    Electronic Resource
    Electronic Resource
    A Structured Light System For Measuring Wounds (1995)
    Oxford UK and Boston, USA : Blackwell Publishers Ltd.
    The @photogrammetric record 15 (1995), S. 0 
    Details
    ISSN: 1477-9730
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying
    Notes: The lack of an accepted method of accurate and objective measurement of wound dimensions is a major obstacle to the assessment of effective wound management regimes. This paper addresses the problems associated with wound measurements and introduces a new instrument based on the principle of coded structured light. The instrument projects a sequence of parallel stripes of light onto the surface of the lesion. These patterns are observed by a video camera which is linked to a computer system where the images can be stored and processed. Using the positions of the focal points of the camera and the stripe projector, the computer calculates a three dimensional map of the observed scene by triangulation. This map is then used to reconstruct the original, healthy skin surface by cubic spline interpolation. The area of the reconstructed surface is the area of the wound. Its volume is sandwiched between the measured and the reconstructed surface. The system also calculates the depth and the circumference of the wound. The instrument measures the volume of the wound with a precision of about 5 per cent provided that the ratio of volume to area is greater than 4 mm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/0031-868X.00025
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  • 9
    Electronic Resource
    Electronic Resource
    Strengthening of Carbon Fibres by Fast Neutron Irradiation (1972)
    [s.l.] : Nature Publishing Group
    Nature 239 (1972), S. 95-96 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the unirradiated condition the fibre exhibited an average fracture strength (af) of 2.86 GNm~2 and a Young's modulus (E) of 215 GNm~2, properties typical for a PAN-based fibre heat treated to about 1,100 C3. The recorded average values of Of and E after several irradiation treatments are ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/239095a0
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  • 10
    Electronic Resource
    Electronic Resource
    Thermal stability of silicon carbide fibres (1975)
    [s.l.] : Nature Publishing Group
    Nature 255 (1975), S. 474-475 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The four pyrolytically deposited silicon carbide fibres which we examined are listed in Table 1 (fibres A-D). The silicon carbide densities of all of the fibres were less than the theoretical values and the fibre coatings had (3 silicon carbide structures with varying amounts of a disordered ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/255474a0
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