Publication Date:
1998-06-06
Description:
The coi1 mutation defines an Arabidopsis gene required for response to jasmonates, which regulate defense against insects and pathogens, wound healing, and pollen fertility. The wild-type allele, COI1, was mapped to a 90-kilobase genomic fragment and located by complementation of coi1-1 mutants. The predicted amino acid sequence of the COI1 protein contains 16 leucine-rich repeats and an F-box motif. It has similarity to the F-box proteins Arabidopsis TIR1, human Skp2, and yeast Grr1, which appear to function by targeting repressor proteins for removal by ubiquitination.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Xie, D X -- Feys, B F -- James, S -- Nieto-Rostro, M -- Turner, J G -- New York, N.Y. -- Science. 1998 May 15;280(5366):1091-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9582125" target="_blank"〉PubMed〈/a〉
Keywords:
Acetates/pharmacology
;
Amino Acid Sequence
;
Arabidopsis/*genetics/growth & development/physiology
;
*Arabidopsis Proteins
;
Chromosome Mapping
;
Cyclopentanes/*metabolism/pharmacology
;
*Genes, Plant
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Genetic Complementation Test
;
Molecular Sequence Data
;
Mutation
;
Open Reading Frames
;
Oxylipins
;
Plant Growth Regulators/*metabolism
;
Plant Proteins/chemistry/*genetics/*physiology
;
Plants, Genetically Modified
;
Polymorphism, Genetic
;
Repressor Proteins/metabolism
;
Signal Transduction
;
Transformation, Genetic
;
Ubiquitins/metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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