ISSN:
1573-5168
Keywords:
elasmobranch
;
catecholamines
;
angiotensin II
;
cardiovascular actions
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The interaction between homologous dogfish angiotensin II ([Asn1, Pro3, Ile5]-AngII) and catecholamines was examined using blood pressure bioassay. Both noradrenaline and [Asn1, Pro3, Ile5]-Ang II elicited a pressor response. Pre-treatment with phentolamine (1 mg kg-1) completely abolished the noradrenaline pressor response but did not alter the magnitude of the [Asn1, Pro3, Ile5]-Ang II pressor response although there was an initial delay in the response to [Asn1, Pro3, Ile5]-Ang II. These results indicate that the Ang II-induced pressor response is a direct Ang II-mediated vascular response in elasmobranchs.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1007795200105
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