ISSN:
1095-8649
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
The primary immune response of brown trout (Salmo trutta L.) was studied after injections of two cellular antigens–Salmonella typhi H, flagellar antigen d, and human group ‘O’Rh+ red blood cells. Both intraperitoneal and intramuscular injections were employed. Agglutinins and complement–fixing antibodies were produced to S. typhi and haem–agglutinins to human ‘O’ red blood cells. Maximum titres to S. typhi were reached after 49 days in the case of both agglutinins and complement-fixing antibody. Haem-agglutinins reached a maximum value of 1 : 512 between 35 and 42 days. Haemagglutinins to human ‘O’ red blood cells were detected as early as 7 days after injection. Antibodies against S. typhi were found after 14 days. Natural haemolysins were present against horse, sheep and human groups ‘A’, ‘B’ and ‘AB’ but not with group ‘O’. No natural haemagglutinins were present to the six types of red blood cells tested. No precipitins were detected to either S. typhi or human ‘O’ red blood cells by immunodiffusion.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1095-8649.1977.tb04042.x
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