ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Emerging studies have showed that silk fibroin might be as a naturally occurringdegradable biomaterial for tissue engineering with unique mechanical properties, biocompatibility and processability. To optimize the formation of the regenerated silk fibroin film, in this study, we examined the genotoxic potential of the regenerated silk fibroin films by different cross-linking mode with micronucleus and the single cell gel electrophoresis (comet) assay. The data showed that MNF in group PC and group SD showed significantly no difference with blank group (P〉0.05), and no evident comet tails were observed. However, the result of EC group was significantly different from the control group(P〈0.01). Taken together, RSFFs in group PC and group SD have no evident genotoxicity, which is better than groupEC
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.257.pdf
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