ISSN:
1420-9071
Keywords:
Acute myelogenous leukemia
;
cell subpopulations
;
cell loss
;
kinetics in culture
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary A kinetic study was performed on leukemic blasts from patients with acute myeloid leukemia, separated into 2 subpopulations by a specific density gradient. The growth curve and the [3H]-thymidine uptake were simultaneously analyzed. While cumulative nucleotide uptake fitted with the growth kinetics in the low-density fraction, such a concordance was not found in the high-density subpopulation. That indicated the occurrence of simultaneous growth and loss in the high density fraction, which could not be evaluated by a simple numerical determination.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01941723
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