ISSN:
1432-1211
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract An antigen reactive with antisera to a human chromosome 7-coded cell-surface antigen can be extracted from human cells with the nonionic detergent NP-40. Immune complexes of radiolabeled cell extracts analyzed on SDS polyacrylamide gels showed a single protein with an apparent M.W. of approximately 165,000. This protein was immunoprecipitated from extracts of hybrid cells containing chromosome 7 and human cell extracts, but not from mouse cell extracts or from extracts of a hybrid clone without human chromosome 7. The data presented here indicate that the protein identified on the gels is a cell-surface glycoprotein coded for by human chromosome 7.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01563921
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