Publication Date:
2018-05-25
Description:
Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation, Published online: 24 May 2018; doi:10.1038/s41467-018-04436-w Myotube formation by fusion of myoblasts is essential for skeletal muscle formation, but which molecules regulate this process remains elusive. Here authors identify the mechanosensitive PIEZO1 channel as a key element, whose activity is regulated by phosphatidylserine during myotube formation.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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