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  • 1
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    Genome of the host-cell transforming parasite Theileria annulata compared with T. parva (2005)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2005-07-05
    Description: Theileria annulata and T. parva are closely related protozoan parasites that cause lymphoproliferative diseases of cattle. We sequenced the genome of T. annulata and compared it with that of T. parva to understand the mechanisms underlying transformation and tropism. Despite high conservation of gene sequences and synteny, the analysis reveals unequally expanded gene families and species-specific genes. We also identify divergent families of putative secreted polypeptides that may reduce immune recognition, candidate regulators of host-cell transformation, and a Theileria-specific protein domain [frequently associated in Theileria (FAINT)] present in a large number of secreted proteins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pain, Arnab -- Renauld, Hubert -- Berriman, Matthew -- Murphy, Lee -- Yeats, Corin A -- Weir, William -- Kerhornou, Arnaud -- Aslett, Martin -- Bishop, Richard -- Bouchier, Christiane -- Cochet, Madeleine -- Coulson, Richard M R -- Cronin, Ann -- de Villiers, Etienne P -- Fraser, Audrey -- Fosker, Nigel -- Gardner, Malcolm -- Goble, Arlette -- Griffiths-Jones, Sam -- Harris, David E -- Katzer, Frank -- Larke, Natasha -- Lord, Angela -- Maser, Pascal -- McKellar, Sue -- Mooney, Paul -- Morton, Fraser -- Nene, Vishvanath -- O'Neil, Susan -- Price, Claire -- Quail, Michael A -- Rabbinowitsch, Ester -- Rawlings, Neil D -- Rutter, Simon -- Saunders, David -- Seeger, Kathy -- Shah, Trushar -- Squares, Robert -- Squares, Steven -- Tivey, Adrian -- Walker, Alan R -- Woodward, John -- Dobbelaere, Dirk A E -- Langsley, Gordon -- Rajandream, Marie-Adele -- McKeever, Declan -- Shiels, Brian -- Tait, Andrew -- Barrell, Bart -- Hall, Neil -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2005 Jul 1;309(5731):131-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK. ap2@sanger.ac.uk〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15994557" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Motifs ; Animals ; Cattle ; Cell Proliferation ; Chromosome Mapping ; Chromosomes/genetics ; Conserved Sequence ; Genes, Protozoan ; *Genome, Protozoan ; Life Cycle Stages ; Lipid Metabolism ; Lymphocytes/cytology/parasitology ; Molecular Sequence Data ; Multigene Family ; Phylogeny ; Protein Sorting Signals/genetics ; Protein Structure, Tertiary ; Proteome ; Protozoan Proteins/chemistry/*genetics/physiology ; Sequence Analysis, DNA ; Species Specificity ; Synteny ; Telomere/genetics ; Theileria annulata/*genetics/growth & development/immunology/pathogenicity ; Theileria parva/*genetics/growth & development/immunology/pathogenicity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Arabidopsis AUX1 gene: a permease-like regulator of root gravitropism (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-08-16
    Description: The plant hormone auxin regulates various developmental processes including root formation, vascular development, and gravitropism. Mutations within the AUX1 gene confer an auxin-resistant root growth phenotype and abolish root gravitropic curvature. Polypeptide sequence similarity to amino acid permeases suggests that AUX1 mediates the transport of an amino acid-like signaling molecule. Indole-3-acetic acid, the major form of auxin in higher plants, is structurally similar to tryptophan and is a likely substrate for the AUX1 gene product. The cloned AUX1 gene can restore the auxin-responsiveness of transgenic aux1 roots. Spatially, AUX1 is expressed in root apical tissues that regulate root gravitropic curvature.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bennett, M J -- Marchant, A -- Green, H G -- May, S T -- Ward, S P -- Millner, P A -- Walker, A R -- Schulz, B -- Feldmann, K A -- New York, N.Y. -- Science. 1996 Aug 16;273(5277):948-50.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8688077" target="_blank"〉PubMed〈/a〉
    Keywords: 2,4-Dichlorophenoxyacetic Acid/pharmacology ; Amino Acid Sequence ; Amino Acid Transport Systems ; Amino Acids/metabolism ; Arabidopsis/chemistry/*genetics/growth & development/metabolism ; *Arabidopsis Proteins ; Biological Transport ; Cloning, Molecular ; DNA, Bacterial/genetics ; *Genes, Plant ; Genetic Complementation Test ; *Gravitropism ; Indoleacetic Acids/metabolism/pharmacology ; Membrane Transport Proteins/chemistry ; Molecular Sequence Data ; Molecular Weight ; Mutation ; Plant Proteins/chemistry/*genetics/metabolism ; Plant Roots/*growth & development/metabolism ; Sequence Alignment ; Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
    Electronic Resource
    Electronic Resource
    Determination of the structure of HBr OCS (1995)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 102 (1995), S. 7298-7305 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The structure of the HBr OCS van der Waals complex has been studied by Fourier transform microwave spectroscopy. The ground state complex is hydrogen bound and quasilinear with SCO–HBr atomic ordering. Spectra from five different isotopomers were observed and assigned. The wide amplitude bending angle of the hydrogen bromide was calculated from the nuclear quadrupole coupling constant χaa to be 25.2°. Second order quadrupole effects, centrifugal distortion in the nuclear quadrupole coupling constant Dχ, a spin–rotation interaction, CBr, and a spin–spin interaction, Daa, were all included in the Hamiltonian. The following spectroscopic constants have been determined for the H79Br OCS isotopomer: B¯=488.7948(4) MHz; DJ=2.167(6) kHz; HJ=1.19(3) Hz; χaa=387.14(1) MHz; Dx=6.79(14) kHz; CBr=0.55(13) kHz; and Daa=7.7(1.2) kHz. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.469041
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  • 4
    Electronic Resource
    Electronic Resource
    Microwave determination of the structure of the Cs conformation of dipropyl ether (1993)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 97 (1993), S. 6979-6982 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100129a010
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  • 5
    Electronic Resource
    Electronic Resource
    Cepheids as Distance Indicators (1987)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 25 (1987), S. 345-375 
    Details
    ISSN: 0066-4146
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.aa.25.090187.002021
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  • 6
    Electronic Resource
    Electronic Resource
    Determination of the structure of HBr DBr (1997)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 106 (1997), S. 6240-6247 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We have investigated the structure and dynamics of the weakly bound complex of the four bromine isotopomers of HBr DBr, using pulsed-jet Fourier transform microwave spectroscopy. In addition, the equilibrium geometry, intermolecular energy, and vibrational force constants for the dimer have been calculated at the MP2 level using a large basis set containing bond functions. In the hydrogen halide dimers, allowed transitions are across the inversion doublet caused by the geared interchange of the donor and acceptor of the hydrogen bond. While in the classic study of (HF)21 it was observed that this splitting results in an inversion frequency in the microwave region of the spectrum, in (HCl)2 and (HBr)2 that the lower inversion barrier, results in an inversion frequency in the infrared. In order to investigate the hydrogen bromide dimer with the high precision allowed by an FT microwave experiment, we have "quenched" the inversion motion by substituting deuterium for one of the hydrogens. The Br–Br distance in the complex is 4.136 Å. Using measurements of the nuclear quadrupole coupling constants of the bromine nuclei, the wide amplitude bending motions of the hydrogen-bonded deuterium have been determined as have the wide amplitude bending angle of the nonbonding hydrogen atom. The Br–Br–D angle undergoes excursions of 28° about zero, and the H–Br–Br angle oscillates 25° about its 90° equilibrium angle. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.474055
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  • 7
    Electronic Resource
    Electronic Resource
    The structure of O3–CH4 and the implications for the O+CH4 precursor-initiated reaction (2000)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 2139-2144 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The rotational spectrum of the O3–CH4 complex has been measured in a molecular beam using a pulsed-nozzle Fourier-transform microwave spectrometer. An a-type pure-rotation and a c-type rotation-inversion electric-dipole spectrum is observed, complicated by the nearly free internal rotation of the CH4 top and the inversion tunneling of the O3. The nuclear-spin statistics of the equivalent oxygen nuclei leads to only one tunneling component existing for each rotation–internal-rotation state, indicating that the transition state has a heavy-atom, C2v-symmetry geometry. The tunneling splitting is determined to be 30 to 40 MHz, dependent on the CH4 internal-rotor state. Only two of the three methane internal-rotor states have been assigned. These two states of A and F symmetry have asymmetric-rotor energy-level structures, weakly perturbed by the ozone-inversion tunneling. The zero-point structure of the complex has a heavy-atom plane of symmetry with the two terminal O atoms equidistant above and below this plane. The angle between the line joining the center of masses of the two subunits and the O3, C2 axis is 118.2(5)°, with the central O directed away from the CH4. The shortest O–C separation is 3.57 Å. The geometry of the complex suggests two outcomes for the reaction of an O atom produced by 267 nm photolysis of O3 in the complex (assuming that the initial O3 photodissociation dynamics are not perturbed by complexation), either nonreaction or reaction by stripping of a hydrogen atom at high impact parameters, leading to fast, highly rotationally excited, OH product. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.482026
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  • 8
    Electronic Resource
    Electronic Resource
    Erratum: Determination of the structure of HBr DBr [J. Chem. Phys. 106, 6240 (1997)] (1997)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 106 (1997), S. 10386-10386 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.474133
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  • 9
    Electronic Resource
    Electronic Resource
    CERTAIN BIOCHEMICAL FINDINGS IN MAN IN RELATION TO DIET (1958)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 69 (1958), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1958.tb49731.x
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  • 10
    Electronic Resource
    Electronic Resource
    Low Niacin Concentration in the Breast Milk of Bantu Mothers on a High-Maize Diet (1954)
    [s.l.] : Nature Publishing Group
    Nature 173 (1954), S. 405-406 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] To throw light on the subject, breast milks from four groups of mothers have been investigated: (1) Urban Bantu mothers in poor circumstances whose consumption of maize meal (90-100 per cent extraction) exceeded 1 lb. per diem, and supplied 65-85 per cent of total calories ; (2) Indian and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/173405a0
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