Publication Date:
1998-08-26
Description:
A fundamental question about human memory is why some experiences are remembered whereas others are forgotten. Brain activation during word encoding was measured using blocked and event-related functional magnetic resonance imaging to examine how neural activation differs for subsequently remembered and subsequently forgotten experiences. Results revealed that the ability to later remember a verbal experience is predicted by the magnitude of activation in left prefrontal and temporal cortices during that experience. These findings provide direct evidence that left prefrontal and temporal regions jointly promote memory formation for verbalizable events.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wagner, A D -- Schacter, D L -- Rotte, M -- Koutstaal, W -- Maril, A -- Dale, A M -- Rosen, B R -- Buckner, R L -- AG05778/AG/NIA NIH HHS/ -- AG08441/AG/NIA NIH HHS/ -- DC03245-02/DC/NIDCD NIH HHS/ -- New York, N.Y. -- Science. 1998 Aug 21;281(5380):1188-91.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Massachusetts General Hospital NMR Center, Harvard Medical School, Charlestown, MA 02129, USA. adwagner@nmr.mgh.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9712582" target="_blank"〉PubMed〈/a〉
Keywords:
Adolescent
;
Adult
;
Brain Mapping
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Memory/*physiology
;
Perception
;
Prefrontal Cortex/*physiology
;
Temporal Lobe/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
Permalink