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  • 1
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    FDA "reform"? (1998)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1998
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Feinstone, S M -- Lewis, A M Jr -- Markoff, L J -- Carbone, K -- Golding, H -- New York, N.Y. -- Science. 1998 Jan 9;279(5348):157-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9446214" target="_blank"〉PubMed〈/a〉
    Keywords: Budgets ; Drug Approval ; Drug Industry ; Drug and Narcotic Control ; *Research Support as Topic ; United States ; United States Food and Drug Administration/*economics/legislation & jurisprudence
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Differential NK cell and macrophage killing of hamster cells infected with nononcogenic or oncogenic adenovirus (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-05-11
    Description: Hamster cells infected with highly oncogenic human adenovirus type 12 (Ad12) were resistant to lysis by natural killer cells and macrophages, compared to cells infected with nononcogenic adenovirus type 2 (Ad2). The data suggest that early adenovirus gene expression in hamster cells results in preferential survival of Ad12, compared to Ad2, infected cells in vivo, thus providing an explanation for the differences in the oncogenicities of these two transforming viruses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cook, J L -- Lewis, A M Jr -- CA 31732/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1984 May 11;224(4649):612-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6710160" target="_blank"〉PubMed〈/a〉
    Keywords: Adenoviruses, Human/*immunology ; Animals ; Cell Transformation, Neoplastic/metabolism ; Cell Transformation, Viral ; Cricetinae ; Humans ; Immunity, Cellular ; Killer Cells, Natural/*physiology ; Macrophages/*physiology ; Mesocricetus ; Oncogenic Viruses/*immunology ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    A new role for DNA virus early proteins in viral carcinogenesis (1985)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1985-01-04
    Description: The T antigen proteins encoded by DNA tumor virus early genes are involved in the transformation of normal cells to immortalized neoplastic cells that may or may not be tumorigenic in immunocompetent animals. Studies have been made of the tumorigenicity of DNA virus-transformed cells and the interactions of these cells in vivo and in vitro with immunologically nonspecific host effector cells such as natural killer cells and macrophages. The results imply that the T proteins determine the capacity of transformed cells to induce tumors by governing the level of susceptibility that transformed cells express to destruction by such host cellular defenses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lewis, A M Jr -- Cook, J L -- CA 31732/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1985 Jan 4;227(4682):15-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3843807" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigens, Polyomavirus Transforming ; Antigens, Viral, Tumor/*metabolism ; Cell Line ; Cell Transformation, Neoplastic/immunology/*metabolism ; *Cell Transformation, Viral ; Cricetinae ; Cytotoxicity, Immunologic ; DNA Viruses/*metabolism ; Humans ; Immunity, Cellular ; Killer Cells, Natural/immunology ; Major Histocompatibility Complex ; Mesocricetus ; Mice ; Mice, Nude ; Neoplasm Transplantation ; Neoplasms, Experimental/immunology ; Rats ; Viral Proteins/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
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