Publication Date:
1992-11-06
Description:
Proteins at the boundary between the cytoskeleton and the plasma membrane control cell shape, delimit specialized membrane domains, and stabilize attachments to other cells and to the substrate. These proteins also regulate cell locomotion and cytoplasmic responses to growth factors and other external stimuli. This diversity of cellular functions is matched by the large number of biochemical mechanisms that mediate the connections between membrane proteins and the underlying cytoskeleton, the so-called membrane skeleton. General organizational themes are beginning to emerge from examination of this biochemical diversity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Luna, E J -- Hitt, A L -- R01 GM033048/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1992 Nov 6;258(5084):955-64.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cell Biology Group, Worcester Foundation for Experimental Biology, Shrewsbury, MA 01545.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1439807" target="_blank"〉PubMed〈/a〉
Keywords:
Cell Adhesion/physiology
;
Cell Membrane/*physiology/ultrastructure
;
Cell Movement/physiology
;
Cell Physiological Phenomena
;
Cells/cytology
;
Cytoskeleton/*physiology/ultrastructure
;
Homeostasis
;
Humans
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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