Publication Date:
1985-09-27
Description:
The retrovirus frequently isolated from patients with the acquired immune deficiency syndrome (AIDS) has two novel open reading frames previously designated "A" and "B." The "A" region was found to be specifically expressed as polyadenylated RNA's of 5.5 and 5.0 kilobases in infected cells. The "B" region was expressed as 1.8- to 2.0-kilobase RNA species. Additional full-length and spliced messenger RNA's of the env region were also identified.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rabson, A B -- Daugherty, D F -- Venkatesan, S -- Boulukos, K E -- Benn, S I -- Folks, T M -- Feorino, P -- Martin, M A -- New York, N.Y. -- Science. 1985 Sep 27;229(4720):1388-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2994220" target="_blank"〉PubMed〈/a〉
Keywords:
Acquired Immunodeficiency Syndrome/*microbiology
;
DNA, Viral/genetics
;
Deltaretrovirus/*genetics
;
Genes, Viral
;
Humans
;
Lymphocytes/*microbiology
;
Nucleic Acid Hybridization
;
RNA, Messenger/genetics
;
RNA, Viral/genetics
;
Repetitive Sequences, Nucleic Acid
;
*Transcription, Genetic
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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