ISSN:
1662-9752
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Scaffold in bone tissue engineering must have a three-dimensional (3-D) interconnectedporous structure acting as a template for bone tissue regeneration, and material fabricating thescaffold must be biocompatible and can provide structural support during bone growth andremodeling at the same time. In this paper, a method of phase separation and particle leachingcombined (PS/PL) was used to prepare porous scaffold of nano-hydroxyapatite and polyamide6(n-HA/PA6) composite. The results show that the scaffold prepared by PS/PL has not onlyinterconnected macropores of 100~300 μm, but also micropores on the walls of macropores, andPS/PL scaffold is more interconnective in compare with phase separation (PS) scaffold. When theporosity of the scaffold is about 79%, its compressive strongth is about 3.27 MPa, that is similar tothe human cancellous bone(2~10MPa). Ethanol has some effect on hydrogen bonds, but fabricatingmethod will not change the chemical component of the composite. The porous scaffold is prospectfor bone tissue engineering
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/02/15/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.544-545.793.pdf
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