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  • 1
    Keywords: Oceanography. ; Energy policy. ; Energy and state. ; Physical geography. ; Water. ; Hydrology. ; Environmental sciences Social aspects. ; Ocean Sciences. ; Energy Policy, Economics and Management. ; Earth System Sciences. ; Water. ; Environmental Social Sciences.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Advantages and Disadvantages of Offshore Wind Energy -- Chapter 3. Research Progress of Offshore Wind Energy -- Chapter 4. Characteristics of Global Offshore Wind Energy -- Chapter 5. Climate Characteristics of Wind Energy in the Maritime Silk Road -- Chapter 6. Long Term Trend of Wind Energy in the Maritime Silk Road -- Chapter 7. Wind Energy Evaluation Around the Sri Lanka Waters -- Chapter 8. Future Focus of Wind Energy Evaluation.
    Abstract: This book aims to establish a wind energy evaluation system, to provide scientific reference for site selection, daily operation and long-term planning of wind power generation, thus to make contribution to breaking the shackles of power shortage. Firstly, it presents the advantages and disadvantages of offshore wind power, then further discusses about the status quo and challenges for wind power programs along the Maritime Silk Road and offer suggestions. A wind energy evaluation system was proposed with the Maritime Silk Road as a case study, including climatic features of wind power (temporal-spatial distribution), long-term climatic trend and mechanism, short-term forecast of wind energy, mid- and long-term projection of wind energy, technology of wind energy evaluation on key point or vital region and offshore wind energy dataset construction, to provide systematic and scientific reference for wind power evaluation and utilization. This book is one of the series of publications on 21st century Maritime Silk Road (shortened as “Maritime Silk Road”). It covers the characteristics of the marine environment and marine renewable energy, remote islands and reefs construction, climate change, early warning of wave disasters, legal escort, marine environment and energy big data construction, etc., contributing to the safe and efficient construction of the Maritime Silk Road. It aims to improve our knowledge of the ocean, thus, to improve the capacity for marine construction, enhance the viability of remote islands and reefs, ease the energy crisis and protect the ecological environment, improve the quality of life of residents along the Maritime Silk Road, and protect the rights, interests of the countries and regions participating in the construction of the Maritime Silk Road. It is a valuable reference for decision-makers, researchers, and marine engineers working in the related fields.
    Type of Medium: Online Resource
    Pages: XX, 177 p. 106 illus., 105 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811641114
    Series Statement: Springer Oceanography,
    DDC: 551.46
    Language: English
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  • 2
    Keywords: Biodiversity. ; Food science. ; Fungi. ; Mycology. ; Microbiology. ; Conservation biology. ; Ecology . ; Climatology. ; Ethnology. ; Biodiversity. ; Food Science. ; Fungi. ; Conservation Biology. ; Climate Sciences. ; Ethnology.
    Description / Table of Contents: Prologue -- Introduction -- 1)Setting the scene -- Biodiversity and cultivation -- 2)Edible ectomycorrhizal fungi and their cultivation in china -- 3)Climate change, biotechnology and mexican neotropical edible ectomycorrhizal mushrooms -- 4)Diversity and importance of edible ectomycorrhizal fungi in guatemala -- 5)Advances in the cultivation of Lactarius deliciosus (saffron milk cap) in new zealand -- 6)Edible mushrooms and their cultural importance in yunnan, china -- 7)Advances in desert truffle mycorrhization and cultivation -- case studies -- 8)Diversity, biogeographic distribution, ecology and ectomycorrhizal relationships of the edible porcini mushrooms (Boletus s. str., Boletaceae) worldwide: state of the art and an annotated check-list -- 9)Recent insights in the phylogeny, species diversity and culinary uses of milkcap genera Lactarius and Lactifluus -- 10)Advances in the cultivation of truffles in canada -- 11)Diversity and ecology of edible mushrooms from patagonia native forests, argentina -- 12)Truffle cultivation in the south of france: socio-economic characteristics -- 13)Ethnomycology in europe: the past, the present, and the future -- ecology with emphasis on wild edible fungi -- 14)Interactions between soil mesofauna and edible ectomycorrhizal mushrooms -- 15)Diversity and importance of edible mushrooms in ectomycorrhizal communities on mexican neotropics -- 16)A checklist of ectomycorrhizal mushrooms associated to Quercus humboldtii in colombia -- 17)Modifications of community structure in ectomycorrhizal artic fungi as a consequence of global warming.
    Abstract: This book focuses on recent advances in our understanding of wild edible mycorrhizal fungi, truffle and mushrooms and their cultivation. In addition to providing fresh insights into various topics, e.g. taxonomy, ecology, cultivation and environmental impact, it also demonstrates the clear but fragile link between wild edible mushrooms and human societies. Comprising 17 chapters written by 41 experts from 13 countries on four continents, it enables readers to grasp the importance of protecting this unique, invaluable, renewable resource in the context of climate change and unprecedented biodiversity loss. The book inspires professionals and encourages young researchers to enter this field to develop the sustainable use of wild edible mushrooms using modern tools and approaches. It also highlights the importance of protecting forested environments, saving species from extinction and generating a significant income for local populations, while keeping alive and renewing the link between humans and wild edible mushrooms so that in the future, the sustainable farming and use of edible mycorrhizal mushrooms will play a predominant role in the management and preservation of forested lands.
    Type of Medium: Online Resource
    Pages: XIV, 480 p. 176 illus., 162 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030373788
    DDC: 333.95
    Language: English
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  • 3
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Cancer. ; Biomedical Research. ; Bioinformatics. ; Cancer Biology.
    Description / Table of Contents: Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.
    Abstract: With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.
    Type of Medium: Online Resource
    Pages: VIII, 247 p. 117 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811544941
    Series Statement: Advances in Experimental Medicine and Biology, 1255
    DDC: 610.72
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Zoology. ; Neurochemistry. ; Neuroscience. ; Zoology. ; Neurochemistry.
    Description / Table of Contents: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.
    Abstract: This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.
    Type of Medium: Online Resource
    Pages: XII, 501 p. 96 illus., 73 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031123900
    Series Statement: Advances in Neurobiology, 29
    DDC: 612.8
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. Economic Importance, Practical Limitations to Production, Management and Breeding Targets of Alfalfa -- Chapter 2. Factors Influencing Yield and Quality -- Chapter 3. The Origin, Evolution and Genetic Diversity of Alfalfa -- Chapter 4. Germplasm Collection, Genetic Resources and Gene Pools in Alfalfa -- Chapter 5. Biotechnology Advances in Alfalfa -- Chapter 6. Sequencing, Assembly and Annotation of the Alfalfa Genome -- Chapter 7. Transcription Factors in Alfalfa (Medicago sativa L.): Genome-Wide Identification and a Web Resource Center AlfalfaTFDB -- Chapter 8. Genomics of Forage Quality in Alfalfa -- Chapter 9. Physiological, Morphological, Biochemical, and Genetic Responses of Alfalfa to Salinity -- Chapter 10. Developing SNPs and Strategies for Genomic Analysis in Alfalfa -- Chapter 11. Genomics Resources for Breeding in Alfalfa: Availability, Utility, and Adoption -- Chapter 12. Genomic Selection for Higher Yield and Quality in Alfalfa -- Chapter 13. Identification and Characterization of Disease Resistance Genes in Alfalfa and Medicago truncatula for Breeding Improved Cultivars -- Chapter 14. Genetic and Genomic Assessments for Improving Drought Resilience in Alfalfa -- Chapter 15. Self-Incompatibility, Inbreeding Depression, and Potential to Develop Inbred Lines in Alfalfa -- Chapter 16. Targeted Mutagenesis of Alfalfa.
    Abstract: This book is the first comprehensive compilation of deliberations on whole genome sequencing of the diploid and tetraploid alfalfa genomes including sequence assembly, gene annotation, and comparative genomics with the model legume genome, functional genomics, and genomics of important agronomic characters. Other chapters describe the genetic diversity and germplasm collections of alfalfa, as well as development of genetic markers and genome-wide association and genomic selection for economical important traits, genome editing, genomics, and breeding targets to address current and future needs. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, breeding, pathology, physiology, molecular genetics and breeding, biotechnology, and structural and functional genomics. The work is also useful to seed and forage industries.
    Type of Medium: Online Resource
    Pages: XXV, 283 p. 64 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030744663
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Food science. ; Food Analysis. ; Chemistry. ; Botany. ; Food Science. ; Food Chemistry. ; Food Studies. ; Plant Science.
    Description / Table of Contents: Aspects morphological, molecular, and biochemical of cinnamon -- The main varieties and producing areas of cinnamon -- The quality evaluation of cinnamon -- Bioactive compounds and extraction methods of cinnamon -- The application of cinnamon as a spice in food -- The antioxidant activity of cinnamon extract and its active components -- The inhibitory effect of cinnamon extract and its active components on bacteria -- The inhibitory effect of cinnamon extract and its active components on fungi -- Inhibition of growth and aflatoxin production by cinnamon -- Effective biocontrol weed with cinnamon oil and extract -- The antiviral effect of cinnamon -- The application potential of cinnamon in the treatment of diabetes -- The application potential of cinnamon in neuroprotection -- The anticancer effect of cinnamon -- Hepatoprotective effect of cinnamon extracts -- Safety evaluation of cinnamon or cinnamon extract.
    Abstract: This work addresses the multiple possibilities for using cinnamon for applications in food science technology and to help in the complimentary treatment and prevention of diseases, with priority given to secondary metabolites produced by this plant. Issues related to the functions of cinnamon and its applications, as well as the biosynthetic pathways of production by plants, are covered in depth. The link between food science and technology and specific medicinal plants has not been explored enough in the current literature, and this text looks to bridge this gap in its extensive coverage of cinnamon. CINNAMON: A Functional Food and Medicinal Plant provides readers with a broad and diverse overview of the importance of secondary metabolites produced by plants and the possibilities for innovative biotechnological approaches that introduce new potential to a wide range of industrial products. The application of cinnamon in products across food science and its numerous health benefits are outlined, including its use as a complimentary medicine for a number of diseases. This book features the main cinnamon varieties and production areas plus quality evaluation and bioactive compound extraction methods. The multiple applications of spices in foods are covered in depth, plus antioxidant activity and inhibitory effects on bacteria and fungi. Beyond its use in foods, readers will find chapters covering the antiviral effects of cinnamon and its use for the treatment and prevention of diabetes and other disorders. Also important is coverage on the safety aspects of cinnamon and its extracts. To date no book has exclusively covered the many uses of cinnamon and cinnamon extracts in food and pharmaceutical applications. This much-needed work provides a fully up to date and extensive overview for researchers to examine the many uses of cinnamon across multiple products and industries. .
    Type of Medium: Online Resource
    Pages: XV, 260 p. 93 illus., 82 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031335051
    Series Statement: Food Bioactive Ingredients,
    DDC: 641.3
    Language: English
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  • 7
    Keywords: Agriculture. ; Plant physiology. ; Photosynthesis. ; Agriculture. ; Plant Physiology. ; Photosynthesis.
    Description / Table of Contents: Preface -- 1. Role of Quantum Dots, Polymeric NPs and Dendrimers in Emphasizing Crops Tolerate Biotic and Abiotic Stresses (Khaled F.M. Salem, Maysoun M. Saleh, Farrag F.B. Abu-Ellail, Heba S. Abbas and Amira S. Mahmoud) -- 2. Climate Change Mitigation and Nanotechnology: An Overview (Asha Kumari, Mahendar Sing Bhinda, Binny Sharma, and Manoj Parihar) -- 3. Nanoparticles: As a New Promising Tool to Increase Plant Immunity (Radwan Khalil, Nesma ElSayed, and Hanan A. Hashem) -- 4. Exploring Nanotechnology to Reduce Stress: Mechanism of Nanomaterial-Mediated Alleviation (Sidra tul Muntha, Mohammad Faizan, Saba Mehreen, and Shareen) -- 5. Alleviation Mechanism of Drought Stress in plants by Metal Nanoparticles - A Perspective Analysis (Iqra Naseer, Sumera Javad, Ajit Singh, Saba Maqsood, Sumera Iqbal, and Khajista Jabeen) -- 6. Role of Various Nanoparticles in Countering Heavy Metal, Salt, and Drought Stress in Plants (Suliman Mohammed Alghanem, Haifa Abdulaziz S. Alhaithloul, Magdi T. Abdelhamid, and Mona H. Soliman) -- 7. Mode of Action and Signaling of Nanoparticles to Alleviate Stress in Crop Plants (Nazish and Babli) -- 8. Impact of Nanoparticles and Nanoparticle-Coated Biomolecules to Ameliorate Salinity Stress in Plants with Special Reference to Physiological, Biochemical and Molecular Mechanism of Action (Akankhya Guru, Soumya Kumar Sahoo, Payel Saha, and Padmanabh Dwivedi) -- 9. Effect of Carbon Nanotubes on Stress Response in Plants: An Overview (Mohammad Faizan, Anjuman Hussain, Anayat Rasool Mir, Vishnu D. Rajput, Tatiana Minkina, and Shamsul Hayat) -- 10. Responses of Crop Plants under Nanoparticles Supply in Alleviating Biotic and Abiotic Stresses (Sameer H. Qari, Awatif M. Abdulmajeed, Taghreed S. Alnusaire, and Mona H. Soliman) -- 11. Nanotechnological Approaches for Efficient Delivery of Plant Ingredients (Maysoun M. Saleh, Amira S. Mahmoud, Heba S. Abbas, Farrag F.B. Abu-Ellail, Muddukrishnaiah Kotakonda, and Khaled F.M. Salem) -- 12. Enhancement of Stress Tolerance of Crop Plants by Zinc Oxide Nanoparticles (Martin Sebesta, Sindy Kurtinova, Marek Kolencik, and Ramakanth Illa) -- 13. Effects of Nanoparticles on Alleviating Phytotoxicity of Soil Heavy Metals: Potential for Enhancing Phytoremediation (Aurang Zeb, Weitao Liu, and Yinlong Zhang) -- 14. Bio-fabricated Silver Nanoparticles: A Sustainable Approach for Augmentation of Plant Growth and Pathogen Control (Amna, Baber Ali, Muhammad Atif Azeem, Ayesha Qayyum, Ghazala Mustafa, Ansar, Muhammad Tariq Javed, and Hassan Javed Chaudhary) -- 15. Nano-Proteomics of Stress Tolerance in Crop Plants (Ghazala Mustafa, Atikah Farooq, Murtaza Hasan, and Amna) -- 16. Role of chitosan nanoparticles in regulation of plant physiology under abiotic stress (Yamshi Arif, Husna Siddiqui and Shamsul Hayat) -- Index.
    Abstract: Nanoscience and nanotechnology imply the study of nanoparticles with at least one dimension below 100 nm with potential for application in a variety of sectors, including in agriculture, therapeutics, diagnostics, engineering, food industry and safety, environmental remediation, and energy infrastructure. This book presents recent developments involving the role of nanoparticles on stress tolerance. In particular, nanoparticles have the potential to provide effective solutions to the multiple agriculture-related problems. Nanoparticles present enhanced reactivity and thus better effectiveness when compared to their bulkier counterparts due to their higher surface-to-volume ratio. In addition, nanoparticles offer the potential to leverage unique surface chemistry as compared to traditional approaches, such that they can be functionalized or grafted with functional groups that can target specific molecules of interest for efficient remediation. Recent findings on the increased use of nanoparticles in agriculture by densely populated countries such as China and India, indicate that this technology may impart a substantial impact on tolerance against stresses, malnutrition, and crop loss. Stresses represent the main constraint for agriculture, affecting plant growth and productivity worldwide. Yield losses in agriculture will be potentiated in the future by global warming, increasing contamination, and reduced availability of fertile land. The challenge of the present and future agriculture is to increase the food supply for a continuously growing human population under environmental conditions that are deteriorating in many areas of the world. This book addresses these issues and many more. Chapters incorporate both theoretical and practical aspects of nanoparticle impacts on plant tolerance against stresses and may serve as baseline information for future research through which significant development is possible. This book will be useful to researchers, instructors and students both in universities and research institutes, especially in relation to biological and agricultural sciences.
    Type of Medium: Online Resource
    Pages: XIV, 421 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030868765
    Series Statement: Sustainable Agriculture Reviews, 53
    DDC: 630
    Language: English
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  • 8
    Keywords: Vertebrates. ; Developmental biology. ; Cytology. ; Vertebrate Zoology. ; Developmental Biology and Stem Cells. ; Cell Biology.
    Description / Table of Contents: 1 Ontogenetic development of the digestive system in golden pompano Trachinotus ovatus -- 2 Food consumption, ingestion and selectivity of golden pompano Trachinotus ovatus larvae, under various rotifer densities -- 3 Weaning regimes for golden pompano Trachinotus ovatus larvae -- 4 Skeleton development and malformation of hatchery-reared golden pompano Trachinotus ovatus -- 5 Nutrition and temperature regulate rearing performance of golden pompano Trachinotus ovatus larvae -- 6 Physical responses of golden pompano Trachinotus ovatus to rearing salinity -- 7 Physiological responses of golden pompano Trachinotus ovatus larvae fingerlings in transportation -- 8 Transcriptional response of golden pompano Trachinotus ovatus larvae to temperature -- 9 IGF genes in golden pompano Trachinotus ovatus larvae -- 10 High water temperature induces jaw deformity and bone morphogenetic proteins (BMPs) gene expression in golden pompano Trachinotus ovatus larvae -- 11 Twist gene in golden pompano Trachinotus ovatus larvae -- 12 Intestinal fatty acid binding protein gene (I-FABP) in golden pompano Trachinotus ovatus larvae -- 13 Effects of water temperature and nutritional manipulation on the expression of liver-type fatty acid-binding protein (L-FABP) gene in golden pompano Trachinotus ovatus larvae -- 14 Follistatin-related protein gene in golden pompano Trachinotus ovatus larvae -- 15 Functional feed additives to the diet of golden pompano Trachinotus ovatus juveniles -- 16 The intestine microbiota community and enzyme activity in Trachinotus ovatus after short-time antibiotic bath administration.
    Abstract: This book highlights the ontogenetic development of larval T. ovatus, provides a comprehensive overview of larval rearing of this species. It focuses on the physiological and molecular changes during the early ontogeny of T. ovatus and hatchery and nursery practices. The first seven chapters update the recent development in the hatchery technology in T. ovatus, including feed and feeding, environmental manipulation, hatchery management, and fingerlings in transportation. Chapter eight and onwards decode the possible molecular mechanisms underlying fish development and response to environmental changes and discuss the transcription and expressions of growth and development-related genes in T. ovatus. The last chapters discuss the functional feed additives to the diet and antibiotic usage of T. ovatus juveniles. This book is a valuable resource for researchers, practitioners and students in the aquaculture industry and related fields.
    Type of Medium: Online Resource
    Pages: VIII, 207 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811917127
    DDC: 596
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Pharmacology. ; Internal medicine. ; Clinical biochemistry. ; Immunology. ; Pharmacology. ; Internal Medicine. ; Medical Biochemistry.
    Description / Table of Contents: Preface -- mRNA-based vaccines and mode of action -- Self-Amplifying mRNA-Based Vaccine Technology and its Mode of Action -- Formulation and Delivery Technologies for mRNA Vaccines -- Messenger RNA-based vaccines against infectious diseases -- Emerge gate for Therapeutics applications of mRNA based drug -- Clinical Development of mRNA Vaccines: Challenges and Opportunities -- Regulatory Considerations on the Development of mRNA Vaccines.
    Abstract: The formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume. The applications of the mRNA technology is covered, focusing on infectious diseases but also touching on other indications, such as immunotherapies and molecular therapies. Potent and long-lasting immune responses observed in animal models, encouraging data from early human clinical studies, together with the success of two mRNA-based COVID-19 vaccines support the use of mRNA-based vaccination as an attractive alternative to conventional vaccine approaches. Consequently, the development progress of the technology, particularly on production, capabilities, and clinical development is reviewed. Topics on safety, regulatory issues, and possible challenges to the mRNA vaccination approach round off this book. Thanks to their high potency, the prospect for generic, low-cost manufacturing processes, and entirely synthetic nature, the future for mRNA vaccines is highly promising. Importantly, mRNA vaccines have the potential to minimize the time between pathogen identification and vaccine release with a huge impact on public health. As the mRNA-based vaccination technology has been progressing rapidly, the book is intended to be an end-to-end review series, covering everything from basic RNA biology and preclinical studies to the manufacturing strategy, clinical development and regulatory approval. It provides established RNA researchers and developers with updates on the latest advancements in the field and allows for a quick but comprehensive overview of this transformative technology, its application, and future potential.
    Type of Medium: Online Resource
    Pages: XI, 205 p. 8 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031180705
    Series Statement: Current Topics in Microbiology and Immunology, 437
    DDC: 571.96
    Language: English
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  • 10
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Telecommunication. ; Oceanography. ; Signal processing. ; Aerospace engineering. ; Astronautics. ; Geographical Information System. ; Communications Engineering, Networks. ; Ocean Sciences. ; Signal, Speech and Image Processing . ; Aerospace Technology and Astronautics.
    Description / Table of Contents: Introduction -- GNSS Signal -- Multipath Propagation -- Modeling and Simulation of GNSS Multipath Signals -- GNSS-R Receiver -- Data Processing for GNSS Reflectometry -- Wind Speed and Direction Retrieval -- Sea Surface Altimetry and Wave Height Estimation -- Sea Ice Detection -- Tsunami Detection and Parameter Estimation -- Snow Depth and Snow Water Equivalent Estimation -- Soil Moisture Retrieval.
    Abstract: This is the first authored English book completely focused on global navigation satellite system reflectometry (GNSS-R). It consists of two main parts: the fundamental theory; and major applications, which include ocean altimetry, sea surface wind speed retrieval, snow depth measurement, soil moisture measurement, tsunami detection and sea ice detection. Striking a healthy balance between theory and practice, and featuring in-depth studies and extensive experimental results, the book introduces beginners to the fundamentals, while preparing experienced researchers to pursue advanced investigations and applications in GNSS-R. .
    Type of Medium: Online Resource
    Pages: XI, 369 p. 257 illus., 244 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811604119
    Series Statement: Navigation: Science and Technology, 9
    DDC: 910.285
    Language: English
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