Publication Date:
2018-11-03
Description:
ARTS mediates apoptosis and regeneration of the intestinal stem cell niche ARTS mediates apoptosis and regeneration of the intestinal stem cell niche, Published online: 02 November 2018; doi:10.1038/s41467-018-06941-4 The mechanisms regulating intestinal stem cell elimination remain unclear. Here, the authors identify that the pro-apoptotic protein ARTS (a Septin4 isoform) interacts with XIAP in the intestinal stem cell niche to regulate stem cell survival during intestinal homeostasis and regeneration.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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