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  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 368-372 (Feb. 2008), p. 1227-1230 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A novel calcium phosphate cement (CPC) was prepared by mixing partially crystallizedcalcium phosphate (PCCP) containing carbonate and dicalcium phosphate anhydrous (DCPA) in thiswork. The effects of the carbonate content on the phase composition, strength, prosity, and degradation ofthe set bodies were studied. The results showed that the cement formed into hydroxyapatite (HAp) aftersetting, in which carbonate doped into the HAp crystal lattice. With the increase of the carbonate tophosphate ratio in PCCP, the compressive strength of the cement declined and the setting of the cementaccelerated. Furthermore, the calcium phosphate cement formed a more porous structure with theincrease of the carbonate to phosphate ratio in PCCP. The results also indicated that the degradation ofCPC may be speeded up by introducing carbonate to the cement
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 330-332 (Feb. 2007), p. 843-846 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study modified starch were used as anti-washout promoters of injectable calciumphosphate cement (CPC) and the effects of the modified starch on the injectability, anti-washoutperformance, setting time, compressive strength, phase evolution and microstructure of this cementwere investigated. The injectability of the cement was improved by adding the modified starch(0.5-2.0%). After mixing with modified starch (0.5-2.0%), the cement showed better anti-washoutperformance than that without modified starch after immersed and shaken in SBF. Especially, whenthe content of the modified starch was 1.0%, the remaining percentage of the cement was reached to92.6%, but only 5.9% of the CPC paste remained and set for the sample without modified starch aftershaken for 2 hrs. The compressive strength of cements significantly increased from 44 MPa to 54MPa when 0.5% of modified starch was added. And a slight increase on the mechanical strength canbe observed for other concentrations. Powder X-ray diffraction analysis revealed no significantdifference for the conversion of the cement to hydroxyapatite for any concentrations of modifiedstarches. The influence of the modified starch on the microstructure of the set cement was alsostudied. The results showed the modified starch would reduce the acicular crystal size ofhydroxyapatite accompanied with little flaky crystals generation and made a compact structure. It isconcluded that modified starch, a suitable anti-washout promoter, improved the performance of CPC
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 336-338 (Apr. 2007), p. 1658-1661 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: An injectable calcium phosphate bone cement was prepared by combining amorphous calciumphosphate (ACP) and dicalcium phosphate dihydrate (DCPD) for use in non-invasive surgery in this work.The effect of the conserving time on the viscosity, yield stress and injectability of the calcium phosphatecement (CPC) pastes were studied. The results showed that as the conserving time of the pastes prolonged,the viscosity and the yield stress of the pastes increased exponentially, and the injectability of the pastesdecreased. This resulted from the transformation of DCPD and ACP into hydroxyapatite via hydrationreaction. The results also indicated that the pastes still exhibited good injectability in even 15 min afterpreparation of the CPC pastes
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 330-332 (Feb. 2007), p. 983-986 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, an ACP-DCPD based Calcium phosphate cement (CPC) scaffold with aporosity of 88% was prepared by using Na3PO4 as a poregen and then modified by collagen andchitosan. The results showed that collagen and chitosan obviously increased the compressivestrength. Cell culture showed that the cell can migrate, attach, proliferate and differentiate on thesurface of the materials and the pores walls. This CPC scaffold modified with collagen or chitosanwas a promising material to be used in bone tissue engineering
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 336-338 (Apr. 2007), p. 1628-1631 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Calcium phosphate cements (CPCs) are well-known orthopedic materials for filling bone.However, CPC pastes tend to disintegrate immediately when contacting with blood or other aqueous(body) fluids, which is a main limitation of its clinical applications in bone repairing, reconstruction andaugmentation. To improve the anti-washout performance of CPC, modified starches such aspre-gelatinized starch, etherified starch, and esterified starch were added to the liquid phase of CPC in thiswork. CPC with good anti-washout performance was prepared and the effects of the modified starches onthe properties of CPC were investigated. The results showed that the CPC with the modified starches weremore stable in simulated body fluid than that without modified starch, especially the CPC with theetherified starch (II). X-ray diffraction analysis revealed that the modified starches did not inhibit CPCcomponents from converting to hydroxyapatite. Furthermore, the anti-washout mechanism of themodified starches in CPC was discussed. It is concluded that the addition of the modified starches such aspre-gelatinized starch, etherified starch, and esterified starch to CPC can improve its anti-washoutperformance and should be of value in clinical surgery where the cement is exposed to blood
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