Publication Date:
2018-09-18
Description:
A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis A plant Bro1 domain protein BRAF regulates multivesicular body biogenesis and membrane protein homeostasis, Published online: 17 September 2018; doi:10.1038/s41467-018-05913-y The ESCRT complex contributes to selective vacuolar degradation of membrane proteins. Here, the authors show that the plant-specific BRAF protein negatively regulates intraluminal vesicle formation and membrane protein degradation by preventing FREE1 binding to the ESCRT-I complex protein Vps23.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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