Publication Date:
2024-06-10
Description:
A new tetramic acid glycoside, aurantoside L (1), was isolated from the sponge Siliquariaspongia
japonica collected at Tsushima Is., Nagasaki Prefecture, Japan. The structure of aurantoside
L (1) composed of a tetramic acid bearing a chlorinated polyene system and a trisaccharide part
was elucidated using spectral analysis. Aurantoside L (1) showed anti-parasitic activity against L.
amazonensis with an IC50 value of 0.74 μM.
Keywords:
aurantosides
;
Siliquariaspongia japonica
;
marine sponge
;
nuclear magnetic resonance
;
mass
;
spectrometry
;
anti-leishmanial activity
;
marine natural products
Repository Name:
National Museum of Natural History, Netherlands
Type:
info:eu-repo/semantics/article
Format:
application/pdf
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