Publikationsdatum:
2018-02-21
Beschreibung:
Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia, Published online: 20 February 2018; doi:10.1038/s41467-018-03170-7 BCL2-inhibitor venetoclax is used to treat relapsed/refractory chronic lymphocytic leukemia (CLL). Here, the authors show the clonal dynamics towards venetoclax resistance by performing whole-exome sequencing of 8 CLL patients undergoing venetoclax treatment.
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
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