Publication Date:
2015-10-14
Description:
Article Das et al . present a novel Bayesian approach called expression Quantitative Trait enhancer Loci (eQTeL), which effectively integrates genetic and epigenetic information to identify combination of regulatory genomic variants underlying expression variance. Using various functional data, the authors show the variants identified by eQTeL are likely to be causal. Nature Communications doi: 10.1038/ncomms9555 Authors: Avinash Das, Michael Morley, Christine S. Moravec, W. H. W. Tang, Hakon Hakonarson, Kenneth B. Margulies, Thomas P. Cappola, Shane Jensen, Sridhar Hannenhalli
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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