ISSN:
1432-1017
Keywords:
Concanavalin A
;
Structural transition
;
Plant glycoprotein
;
Protein adsorption
;
Mica plate
;
Force surface apparatus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Abstract The structure of the β-sheet rich molecule, concanavalin A (Con A), shows complicated behaviour when mechanical stress is imposed on adsorbed Con A layers. In the pH range 3.9 to 7.4, the structural changes are dependent on the pH and ionic strength of the solution at the liquid/solid interface. Several molecular shapes are observed ranging from a highly unfolded state characterized by a 1.25 nm thickness of each expelled layer at pH 3.9 to other states with various layer thicknesses at pH 6–7.4 and at a low ionic strength (〈 10−4). In the pH range 6 to 7.4, different molecular species appear to be present.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00185780
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