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  • 1
    Electronic Resource
    Electronic Resource
    P-CENTERS ON BITREES (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of regional science 24 (1984), S. 0 
    Details
    ISSN: 1467-9787
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geography , Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-9787.1984.tb01032.x
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  • 2
    Electronic Resource
    Electronic Resource
    22-kHz calls by isolated rats (1977)
    [s.l.] : Nature Publishing Group
    Nature 265 (1977), S. 236-238 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The experiments reported here mainly involved round-the-clock recording of calls made by socially isolated, adult Wistar rats. Before observation each animal was entrained for at least 1 month to the light-dark schedule under which it was observed. During observation each animal was kept alone in ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/265236a0
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  • 3
    Electronic Resource
    Electronic Resource
    The shape, expansion rate and distance of supernova 1993J from VLBI measurements (1994)
    [s.l.] : Nature Publishing Group
    Nature 368 (1994), S. 610-613 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Our measurements were made with a global VLBI array of between 9 and 15 antennas, observing for up to 18 h at one to four frequencies at each of three epochs (Table 1). We correlated the data from a large subarray of antennas, representing 30% of all the data, at Haystack Observatory; the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/368610a0
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  • 4
    Electronic Resource
    Electronic Resource
    Clinical Evaluation of an Automatic Blood Pressure Controller During Cardiac Surgery (1997)
    Springer
    Journal of clinical monitoring and computing 13 (1997), S. 261-268 
    Details
    ISSN: 1573-2614
    Keywords: computer controlled infusion ; closed loop control ; nitroprusside ; MAP ; anesthesia ; cardiac surgery ; clinical evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine
    Notes: Abstract Objective. During surgery, computers can be of great use to support theanesthesiologist in providing task automation. In this paper we describe aclosed loop blood pressure controller and show the results of its clinicalevaluation. Methods. The controller is based on a simple and robustProportional-Integral controller and a supervising, rule based, expert system.Adaptive control is necessary because the sensitivity of the patients tosodium nitroprusside varies over a wide range. Thirty-three clinical testsduring cardiac surgery, including the cardiopulmonary bypass phase, wereperformed. Results. On average the controller was in automatic mode for 90.6± 9.6% of the time. The performance during automatic control showed themean arterial pressure to be within 10 mmHg of the setpoint for 71.4 ±15.5% of the time. The average absolute distance to the setpoint was 8.1± 7.2 mmHg. Conclusions. The overall performance of the controller wasnoted as very satisfactory by the anesthesiologists.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007389631055
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  • 5
    Electronic Resource
    Electronic Resource
    The First Object Oriented Monitor for Intravenous Anesthesia (2000)
    Springer
    Journal of clinical monitoring and computing 16 (2000), S. 3-10 
    Details
    ISSN: 1573-2614
    Keywords: Field: intravenous anesthesia ; Field: cardiac surgery ; Field: intensive care unit ; Material: personal computer ; Material: workstation ; Monitoring: drug delivery system ; Monitoring: data acquisition ; Monitoring: computer controlled infusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine
    Notes: Abstract Objective.To describe the design and implementation of“INFUSION TOOLBOX,” a software tool to control and monitormultiple intravenous drug infusions simultaneously using pharmacokinetic andpharmacodynamic principles. Methods.INFUSION TOOLBOX has been designedto present a graphical interface. Object Oriented design was used and thesoftware was implemented using Smalltalk, to run on a PC. Basic tools areavailable to manage patient, drugs, pumps and reports. These tools are thePatientPanel, the DrugPanel, the PumpPaneland theHistoryPanel. The screen is built dynamically. The panels may becollapsed or closed to avoid a crowded display. We also built control panelssuch as the Target ControlPanelwhich calculates the best infusionsequence to bring the drug concentration in the plasma compartment to a presetvalue. Before drug delivery, the user enters the patient’s data, selectsa drug, enters its dilution factor and chooses a pharmacokinetic model. Thecalculated plasma concentration is continually displayed and updated. Theanesthetist may ask for the history of the delivery to obtain a graphic reportor to add events to the logbook. A panel targeting the effect is used when apharmacodynamic model is known. Data files for drugs, pumps and surgery areupgradable. Discussion.By creating a resizeable ControlPanelwe enable the anesthetist to display the information he wishes, when hewishes it. The available panels are diverse enough to meet the anesthetistneeds; they may be adapted to the drug used, pumps used and surgery. It is theanesthetist who builds dynamically its different control screens.Conclusion.By adopting an evolutionary solution model we have achievedconsiderable success in building our drug delivery monitor. In addition wehave gained valuable insight into the anesthesia information domain that willallow us to further enhance and expand the system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009904805940
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  • 6
    Electronic Resource
    Electronic Resource
    Efficiency in integral facility design problems (1980)
    Springer
    Journal of optimization theory and applications 32 (1980), S. 135-149 
    Details
    ISSN: 1573-2878
    Keywords: Multiobjective optimization ; efficiency ; facilities design ; design problems
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract An example of design might be a warehouse floor (represented by a setS) of areaA, with unspecified shape. Givenm warehouse users, we suppose that useri has a known disutility functionf isuch thatH i(S), the integral off iover the setS (for example, total travel distance), defines the disutility of the designS to useri. For the vectorH(S) with entriesH i(S), we study the vector minimization problem over the set {H(S) :S a design} and call a design efficient if and only if it solves this problem. Assuming a mild regularity condition, we give necessary and sufficient conditions for a design to be efficient, as well as verifiable conditions for the regularity condition to hold. For the case wheref iis thel p-distance from warehouse docki, with 1〈p〈∞, a design is efficient if and only if it is essentially the same as a contour set of some Steiner-Weber functionf λ=λ1 f 1+⋯+λ m f m ,when the λ i are nonnegative constants, not all zero.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00934720
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  • 7
    Electronic Resource
    Electronic Resource
    Book reviews (1986)
    Springer
    Mathematical methods of operations research 30 (1986), S. A243 
    Details
    ISSN: 1432-5217
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01919296
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  • 8
    Electronic Resource
    Electronic Resource
    Duality relationships for a nonlinear version of the generalized Neyman-Pearson problem (1973)
    Springer
    Journal of optimization theory and applications 11 (1973), S. 360-378 
    Details
    ISSN: 1573-2878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The nonlinear generalized Neyman-Pearson problem examined herein may be considered to be a calculus-of-variations analog of a type of bounded-variable convex-programming problem. By using an approach similar to the Lagrange duality theorem, but taking advantage of the properties of convex and concave functionals, duality relationships somewhat analogous to those of linear programming are developed. Necessary and sufficient conditions are obtained for a solution to the primal problem and for a solution to the dual problem. Also, an example is presented to illustrate some of the results obtained.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00932486
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  • 9
    Electronic Resource
    Electronic Resource
    On characterizing supremum andl p -efficient facility designs (1981)
    Springer
    Journal of optimization theory and applications 35 (1981), S. 129-141 
    Details
    ISSN: 1573-2878
    Keywords: Multi-objective optimization ; efficiency ; facilities design
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Define a design to be any planar setD of known areaa, but of unknown shape and location; more generally, a design can be any set inR d of measurea. For example, a design might be one floor of a warehouse, or a sports arena of known seating capacity. Suppose that the design has, say,m users, or evaluators, with user/evaluatori having a design disutility functionu i , 1≤i≤m, which can be defined for all points in the plane independently of the designs of interest. Given any designD, denote byG i (D) the disutility ofD to user/evaluatori where, by definition,G i (D) is the supremum ofu i over the setD, 1≤i≤m. LetG(D) be the vector with entriesG i (D), 1≤i≤m, and define a design to be efficient if it solves the vector minimization problem obtained using the set of vectors {G(D):D a design}. Given mild assumptions about the disutility functions, and a slight refinement of the design definition to rule out certain pathologies, we present necessary and sufficient conditions for a design to be efficient, and study properties of efficient designs. In the final section, we extend the analysis to more generall p -measures of design disutility.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00934708
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  • 10
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    Demand Point Aggregation for Planar Covering Location Models (2005)
    Springer
    Details
    Publication Date: 2005-04-01
    Print ISSN: 0254-5330
    Electronic ISSN: 1572-9338
    Topics: Mathematics , Economics
    Published by Springer
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