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  • 1
    Publication Date: 2019-08-27
    Description: Non-invasive measuring devices responsive to changes in a patient's intracranial pressure (ICP) can be accurately calibrated for monitoring purposes by providing known changes in ICP by non-invasive methods, such as placing the patient on a tilting bed and calculating a change in ICP from the tilt angle and the length of the patient's cerebrospinal column, or by placing a pressurized skull cap on the patient and measuring the inflation pressure. Absolute values for the patient's pressure-volume index (PVI) and the steady state ICP can then be determined by inducing two known changes in the volume of cerebrospinal fluid while recording the corresponding changes in ICP by means of the calibrated measuring device. The two pairs of data for pressure change and volume change are entered into an equation developed from an equation describing the relationship between ICP and cerebrospinal fluid volume. PVI and steady state ICP are then determined by solving the equation. Methods for inducing known changes in cerebrospinal fluid volume are described.
    Keywords: Life Sciences (General)
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  • 2
    Publication Date: 2019-08-28
    Description: An acoustic nonlinearity parameter (.beta.) measurement method and system for Non-Destructive Evaluation (NDE) of materials and structural members novelly employs a loosely mounted dielectric electrostatic ultrasonic transducer (DEUT) to receive and convert ultrasonic energy into an electrical signal which can be analyzed to determine the .beta. of the test material. The dielectric material is ferroelectric with a high dielectric constant .di-elect cons.. A computer-controlled measurement system coupled to the DEUT contains an excitation signal generator section and a measurement and analysis section. As a result, the DEUT measures the absolute particle displacement amplitudes in test material, leading to derivation of the nonlinearity parameter (.beta.) without the costly, low field reliability methods of the prior art.
    Keywords: Quality Assurance and Reliability
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  • 3
    Publication Date: 2019-08-28
    Description: A tracking generator 21 is slaved to a spectrum analyzer 23 to produce an input signal having a frequency that follows the frequency of the spectrum analyzer sweeping local oscillator 22. The input signal is gated to a transducer 26 by a transmitter gate 25 to produce ultrasonic waves in the sample 28. The resulting ultrasonic echoes are converted into electrical signals by the transducer and then gated into the spectrum analyzer by receiver gate 29. This arrangement produces spectra that are equivalent to shock-exciting the transducer with a true delta function shock-excitation.
    Keywords: Electronics and Electrical Engineering
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  • 4
    Publication Date: 2019-08-28
    Description: A method is presented for determining diastolic intracranial pressure (ICP) in a patient. A first change in the length of a path across the skull of the patient caused by a known change in ICP is measured and used to determine an elasticity constant for the patient. Next, a second change in the length of the path across the patient's skull occurring between systolic and diastolic portions of the patient's heartbeat is measured. The patient's diastolic ICP is a function of the elasticity constant and the second change.
    Keywords: Life Sciences (General)
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  • 5
    Publication Date: 2019-08-28
    Description: A system for and method of detecting and measuring concentrations of an ultrasonically-reflective microsphere contrast agent involving detecting non-linear sum and difference beat frequencies produced by the microspheres when two impinging signals with non-identical frequencies are combined by mixing. These beat frequencies can be used for a variety of applications such as detecting the presence of and measuring the flow rates of biological fluids and industrial liquids, including determining the concentration level of microspheres in the myocardium.
    Keywords: Life Sciences (General)
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