ISSN:
0021-9541
Schlagwort(e):
Life and Medical Sciences
;
Cell & Developmental Biology
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Biologie
,
Medizin
Notizen:
A culture method is proposed for the in vitro development of chicken erythrocytic progenitors. When grown with avian erythropoietin, Colony Forming Unit Erythrocytic (CFU-E) and Burst Forming Unit-Erythrocytic (BFU-E) give rise respectively to erythrocytic colonies and bursts within 3 and 6 days. BFU-E development is greatly enhanced by pokeweed-mitogen-spleen-cell-conditioned medium and requires higher erythropoietin concentrations than for CFU-E. An antigen specific to immature red cells can be detected on CFU-E but not on BFU-E, showing that both progenitors represent distinct entities. BFU-E and CFU-E are found in embryonic marrow and yolk sac. In the young blastoderm BFU-E becomes detectable at the primitive streak stage.
Zusätzliches Material:
8 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jcp.1041050320
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