ISSN:
1432-041X
Keywords:
Key words Amphioxus
;
Zebrafish
;
BF-1
;
Somites
;
Telencephalon
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The forkhead domain containing transcription factor BF-1 has been shown to play a major role in the correct development of the cerebral hemispheres in the mouse. BF-1 orthologs have been isolated from zebrafish and the cephalocordate amphioxus. In both species, BF-1 is expressed in the anterior neural tube. In zebrafish zBF-1 expression is restricted to anterior portions of the otic vesicle and to the presumptive telencephalon. In amphioxus AmphiBF-1 is transiently seen in the frontal part of the first somite and, at 3 days of development, in a small number of cells in the cerebral vesicle (cv). The anterior expression of BF-1 in chordates and vertebrates and of slp-1/2 in Drosophila suggests that BF-1 is crucial for an evolutionarily conserved specification of anterior neuronal cell types.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004270050200
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