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  • 1
    Schlagwort(e): Regenerative medicine. ; Biomedical engineering. ; Biotechnology. ; Mechanical engineering. ; Mathematics Data processing. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Biotechnology. ; Mechanical Engineering. ; Computational Science and Engineering.
    Beschreibung / Inhaltsverzeichnis: Part I: Biological Characterization of Bone Tissue -- Chapter 1. Bone: functions, structure and physiology -- Chapter 2. Bone Quality Assessment at the Atomic Scale -- Part II: Bone Remodelling algorithms -- Chapter 3. Meshless, Bone Remodelling and Bone Regeneration Modelling -- Chapter 4. Dynamic biochemical and cellular models of bone physiology: integrating remodeling processes, tumor growth and therapy -- Chapter 5. Mathematical Modelling of Spatio-Temporal cell dynamics observed during Bone Remodelling -- Chapter 6. A Mechanostatistical Approach to Multiscale Computational Bone Remodelling -- Part III: Numerical simulation of bone tissue and adjacent structures -- Chapter 7. Finite Element Analysis of Bone and Experimental Validation -- Chapter 8. Computational modelling of tissue engineered cartilage constructs -- Chapter 9. On the Computational Biomechanics of the Intervertebral Disc -- Index.
    Kurzfassung: This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.
    Materialart: Online-Ressource
    Seiten: XIV, 241 p. 68 illus., 45 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030375416
    Serie: Lecture Notes in Computational Vision and Biomechanics, 35
    DDC: 612.028
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Schlagwort(e): Geology. ; Sedimentology. ; Geodynamics. ; Geology. ; Sedimentology. ; Geodynamics.
    Beschreibung / Inhaltsverzeichnis: The geological setting of the Moroccan High Atlas and its plate tectonics context -- Structure of the Central High Atlas (Morocco). Constraints from potential field data and 3D models -- Magnetic properties of the remagnetized carbonates of the Central High Atlas (Morocco) -- Paleomagnetism of the Central High Atlas. The widespread Cretaceous Remagnetization and structural implications -- Geodynamic evolution during the Mesozoic and Cenozoic in the Central High Atlas of Morocco from Anisotropy of Magnetic Susceptibility -- Kinematics of structures and basin evolution in the Central High Atlas. Constraints from AMS and paleomagnetic data.
    Kurzfassung: This book presents a significant amount of structural, paleomagnetic and magnetic fabric data in the Central High Atlas (Morocco). The authors thoroughly described and analyzed the present-day structure of this intraplate chain through 22 of cross-sections, potential field data analysis and 3D reconstruction. In addition, the authors propose a palinspastic reconstruction of the structure of the basin at 100 Ma (i.e., post-extension and pre-compression) to finally evaluate its Mesozoic and Cenozoic geodynamic evolution. This books presents (1) a unique three-dimensional model at the chain scale, (2) an analysis of the ca. 100 Ma remagnetization, to perform palinspastic restorations of most representative structures, (3) as well as the interpretation of the magnetic fabrics in order to unravel the tectonic or deformation setting that the rocks underwent in different parts of the basin. This book is of interest to structural geologists in Northern Africa, the Mediterranean and Iberia, as well as to those interested in inverted intraplate basins and paleomagnetists from around the planet. Also, this book is intended to help students to understand better the geological evolution of the Atlas and therefore Morocco and surrounding areas.
    Materialart: Online-Ressource
    Seiten: XXII, 646 p. 324 illus., 311 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031166938
    Serie: Springer Geology,
    DDC: 551
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Signatur: SR 90.0016(274)
    In: Mitteilungen aus dem Geologischen Institut der Eidgenössischen Technischen Hochschule und der Universität Zürich. N.F.
    Materialart: Schriftenreihen ausleihbar
    Seiten: 193 S. + 5 Kt.-Beil.
    Serie: Mitteilungen aus dem Geologischen Institut der Eidgenössischen Technischen Hochschule und der Universität Zürich N.F., 274
    Sprache: Englisch
    Standort: Kompaktmagazin unten
    Zweigbibliothek: GFZ Bibliothek
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Publikationsdatum: 2022-08-30
    Beschreibung: Understanding the impact of long-term exposure of microorganisms to space is critical in understanding how these exposures impact the evolution and adaptation of microbial life under space conditions. In this work we subjected Nostoc sp. CCCryo 231-06, a cyanobacterium capable of living under many different ecological conditions, and also surviving in extreme ones, to a 23-month stay at the International Space Station (the Biology and Mars Experiment, BIOMEX, on the EXPOSE-R2 platform) and returned it to Earth for single-cell genome analysis. We used microfluidic technology and single cell sequencing to identify the changes that occurred in the whole genome of single Nostoc cells. The variant profile showed that biofilm and photosystem associated loci were the most altered, with an increased variant rate of synonymous base pair substitutions. The cause(s) of these non-random alterations and their implications to the evolutionary potential of single bacterial cells under long-term cosmic exposure warrants further investigation.
    Materialart: info:eu-repo/semantics/article
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Publikationsdatum: 2022-07-06
    Beschreibung: The Nostoc sp. strain CCCryo 231-06 is a cyanobacterial strain capable of surviving under extreme conditions and thus is of great interest for the astrobiology community. The knowledge of its complete genome sequence would serve as a guide for further studies. However, a major concern has been placed on the effects of contamination on the quality of sequencing data without a reference genome. Here,we report the use ofmicrofluidic technology combinedwith single cell sequencing and de novo assembly tominimize the contamination and recover the complete genome of the Nostoc strain CCCryo 231-06 with high quality. 100% of the whole genome was recovered with all contaminants removed and a strongly supported phylogenetic tree. The data reported can be useful for comparative genomics for phylogenetic and taxonomic studies. The method used in this work can be applied to studies that require high-quality assemblies of genomes of unknown microorganisms.
    Materialart: info:eu-repo/semantics/article
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    facet.materialart.
    Unbekannt
    In:  Life
    Publikationsdatum: 2023-07-12
    Beschreibung: Motility is a great biosignature and its pattern is characteristic for specific microbes. However, motion does also occur within the cell by the myriads of ongoing processes within the cell and the exchange of gases and nutrients with the outside environment. Here, we propose that the sum of these processes in a microbial cell is equivalent to a pulse in complex organisms and suggest a first approach to measure the “living pulse” in microorganisms. We emphasize that if a “living pulse” can be shown to exist, it would have far-reaching applications, such as for finding life in extreme environments on Earth and in extraterrestrial locations, as well as making sure that life is not present where it should not be, such as during medical procedures and in the food processing industry.
    Sprache: Englisch
    Materialart: info:eu-repo/semantics/article
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  Supplement to: Norder, Sietze Johannes; Proios, Kostas V; Whittaker, Robert J; Alonso, María R; Borges, Paulo A V; Borregaard, Michael K; Cowie, Robert H; Florens, F B Vincent; de Frias Martins, António M; Ibáñez, Miguel; Kissling, W Daniel; de Nascimento, Lea; Otto, Rüdiger; Parent, Christine E; Rigal, François; Warren, Ben H; Fernández-Palacios, José María; van Loon, E Emiel; Triantis, Kostas A; Rijsdijk, Kenneth F (2018): Beyond the Last Glacial Maximum: Island endemism is best explained by long-lasting archipelago configurations. Global Ecology and Biogeography, https://doi.org/10.1111/geb.12835
    Publikationsdatum: 2023-01-13
    Beschreibung: Aim: To quantify the influence of past archipelago configuration on present-day insular biodiversity patterns, and to compare the role of long-lasting archipelago configurations over the Pleistocene to configurations of short duration such as at the Last Glacial Maximum (LGM) and the present-day. Location: 53 volcanic oceanic islands from 12 archipelagos worldwide - Azores, Canary Islands, Cook Islands, Galápagos, Gulf of Guinea, Hawaii, Madeira, Mascarenes, Pitcairn, Revillagigedo, Samoan Islands, and Tristan da Cunha. Time period: The last 800 Kyr, representing the nine most recent glacial-interglacial cycles. Major taxa studied: Land snails and angiosperms. Methods: Species richness data for land snails and angiosperms were compiled from existing literature and species checklists. We reconstructed archipelago configurations at the following sea-levels: the present-day high interglacial sea-level, the intermediate sea-levels that are representative of the Pleistocene, and the low sea-levels of the LGM. We fitted two alternative linear mixed models for each archipelago configuration on the number of single-island endemic, multiple-island endemic, and native non-endemic species. Model performance was assessed based on the goodness-of-fit of the full model, the variance explained by archipelago configuration, and model parsimony. Results: Single-island endemic richness in both taxonomic groups was best explained by intermediate palaeo-configuration (positively by area change, and negatively by palaeo-connectedness), whereas non-endemic native species richness was poorly explained by palaeo-configuration. Single-island endemic richness was better explained by intermediate archipelago configurations than by the archipelago configurations of the LGM or present-day. Main conclusions: Archipelago configurations at intermediate sea-levels - which are representative of the Pleistocene - have left a stronger imprint on single-island endemic richness patterns on volcanic oceanic islands than extreme archipelago configurations that persisted for only a few thousand years (such as the LGM). In understanding ecological and evolutionary dynamics of insular biota it is essential to consider longer-lasting environmental conditions, rather than extreme situations alone.
    Schlagwort(e): Angiosperm species richness; Area/locality; Distance; Land snail species richness; LATITUDE; Log info; LONGITUDE; Number
    Materialart: Dataset
    Format: text/tab-separated-values, 1166 data points
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Publikationsdatum: 2023-06-27
    Schlagwort(e): Age, 14C AMS; Age, dated; Age, dated standard deviation; Bransfield Strait; Depth, bottom/max; DEPTH, sediment/rock; Depth, top/min; GC; GEBRA-93; GEBRA-93-2; Gravity corer; Hespérides
    Materialart: Dataset
    Format: text/tab-separated-values, 12 data points
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Publikationsdatum: 2023-06-27
    Schlagwort(e): Age, 14C AMS; Age, dated; Age, dated standard deviation; Bransfield Strait; Depth, bottom/max; DEPTH, sediment/rock; Depth, top/min; GC; GEBRA-93; GEBRA-93-1; Gravity corer; Hespérides
    Materialart: Dataset
    Format: text/tab-separated-values, 12 data points
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Publikationsdatum: 2023-06-27
    Schlagwort(e): Bransfield Strait; Counting, radiolarians; DEPTH, sediment/rock; GC; GEBRA-93; GEBRA-93-1; Gravity corer; Hespérides; Lithomelissa spp.; Phormacantha group; Radiolarians; Radiolarians, circumpolar group
    Materialart: Dataset
    Format: text/tab-separated-values, 104 data points
    Standort Signatur Erwartet Verfügbarkeit
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