ISSN:
1573-8221
Schlagwort(e):
BCG vaccine
;
SV 40 virus
;
antitumor resistance
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Abstract The duration of the inhibitory effect of BCG vaccine on antitumor immunity induced by SV 40 virus in Syrian hamsters and the possibility of restoring immunity after vaccination were investigated. Specific resistance in animals immunized with SV 40 virus and then inoculated with BCG remained inhibited for 1 year after vaccination. A further injection of SV 40 virus into hamsters previously subjected to combined immunization reinduced specific immunity in the animals to tumors. The results show that the phenomenon of abolition of specific antitumor resistance by BCG vaccine is probably cellular in nature.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00845040
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