ISSN:
0030-493X
Schlagwort(e):
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Fragmentations of N-benzyloxycarbonyl-protected tetrapeptide ethyl esters containing L-alanine and L-proline, in which changes in the numbers and positions of prolyl residues were observed, were studied by negative-ion fast atom bombardment mass spectrometry. A significant difference was found among the abundances of the molecule ions and the fragment ions formed by the cleavage of the benzyloxycarbonyl group, depending on the numbers and positions of prolyl residues in the derivatives. The results indicate that the conformational differences in the tetrapeptide derivatives due to the existence of proline affect fragmentations of molecules in the solution phase in negative-ion fast atom bombardment mass spectrometry.
Zusätzliches Material:
2 Tab.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/oms.1210290407
Permalink