ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Osseointegrated titanium implants have been widely used in clinics for replacement ofmissing teeth. However, sensory perception thresholds of implants were 10 to 100 times higher thanthose of natural teeth. The purpose of this study was to evaluate the effect of the ceramic coatinggenerated by microarc oxidation (MAO) on sensory reconstruction around dental implants. TheMAO coating was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM),and scanning probe microscope (SPM). Moreover, the chemical composition was analyzed with anenergy dispersive spectroscope (EDS). Using smooth titanium discs as a control, Schwann cellresponses to the coating were evaluated by SEM, MTT assay, total protein content and leakage ofcytosolic lactate dehydrogenase (LDH) activity. In addition, the amount of brain-derivedneurotrophic factor (BDNF) secreted by Schwann cells was measured by Enzyme-LinkedImmunosorbent Assay (ELISA). It was observed that the porous coating had separated andhomogeneous micropores in the diameter of 1-2 μm. The concentrations of Ca and P in the layerwere 8.63% and 5.23% respectively. The cell morphology, proliferation and secretion of BDNFwere unaffected. The results indicated that the MAO ceramic coating developed on the surface ofpure titanium had good biocompatibility with Schwann cells for sensory reconstruction arounddental implants
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/54/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.342-343.697.pdf
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