ISSN:
1432-041X
Keywords:
Key words Organogenesis
;
Embryonic lethal mutations
;
Enhancer trap
;
LacZ staining
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract To identify X chromosomal genes required for salivary gland development in the Drosophila embryo, we screened embryos hemizygous for EMS-induced lethal mutations to find mutations causing gross morphological defects in salivary gland development. The parental strain carried a lac Z transgene on the second chromosome, which was specifically expressed in the salivary glands so the mutations could be unambiguously identified. Embryos from 3,383 lines were tested for salivary gland abnormalities following lacZ staining. From 63 lines exhibiting aberrant salivary gland phenotypes, 52 stable lines were established containing mutations affecting salivary gland development. From these, 39 lines could be assigned to nine complementation groups: armadillo, brinker, folded gastrulation, giant, hindsight, Notch, runt, stardust and twisted gastrulation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004270000096
Permalink