ISSN:
0009-2940
Keywords:
Phosphine
;
Phosphinomethylation
;
Phase-transfer catalysis
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Linear Oligophosphaalkanes, XXV1. - Synthesis of Ph2P—CH2—PH2 and (Ph2P—CH2)2PH by Phosphinomethylation of PH3 with Phase-Transfer CatalysisAlkylation of Ph2PH with CH2Cl2 under phase-transfer conditions in the system dichloromethane/toluene/water affords Ph2P-CH2Cl in high yields. Depending on the reaction conditions employed Ph2P-CH2Cl reacts with PH3 in the two phase system under phase-transfer catalysis (nBu4NCl) to yield the tertiary-primary methylenebis(phosphane) Ph2P-CH2-Ph2 (2) or the PH functional triphosphaalkane Ph2P-CH2-PH-CH2-PPh2 (3), respectively. Metallation of 2 and 3 with RLi (R = nBu, tBu) and subsequent reaction with Me3siCl yields the silyl derivatives 2e and 3b, respectively. The analysis of the 1H- 13C- and 31P-NMR spectra is reported.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19901230511
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