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  • 1
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    The theoretical instability strip of M dwarf stars (2014)
    Oxford University Press
    Details
    Publication Date: 2014-02-15
    Description: The overstability of the fundamental radial mode in M dwarf models was theoretically predicted recently by Rodríguez-López et al. The periods were found to be in the ranges ~25–40 min and ~4–8 h, depending on stellar age and excitation mechanism. We have extended our initial M dwarf model grid in mass, metallicity and mixing length parameter. We have also considered models with boundary conditions from phoenix N ext G en atmospheres to test their influence on the pulsation spectra. We find instability of non-radial modes with radial orders up to k  = 3, degree  = 0–3, including p- and g-modes, with the period range extending from 20 min up to 11 h. Furthermore, we find theoretical evidence of the potential of M dwarfs as solar-like oscillators.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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  • 2
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    Functionally defective germline variants of sialic acid acetylesterase in autoimmunity (2010)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2010-06-18
    Description: Sialic acid acetylesterase (SIAE) is an enzyme that negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of immunological tolerance in mice. Heterozygous loss-of-function germline rare variants and a homozygous defective polymorphic variant of SIAE were identified in 24/923 subjects of European origin with relatively common autoimmune disorders and in 2/648 controls of European origin. All heterozygous loss-of-function SIAE mutations tested were capable of functioning in a dominant negative manner. A homozygous secretion-defective polymorphic variant of SIAE was catalytically active, lacked the ability to function in a dominant negative manner, and was seen in eight autoimmune subjects but in no control subjects. The odds ratio for inheriting defective SIAE alleles was 8.6 in all autoimmune subjects, 8.3 in subjects with rheumatoid arthritis, and 7.9 in subjects with type I diabetes. Functionally defective SIAE rare and polymorphic variants represent a strong genetic link to susceptibility in relatively common human autoimmune disorders.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900412/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900412/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Surolia, Ira -- Pirnie, Stephan P -- Chellappa, Vasant -- Taylor, Kendra N -- Cariappa, Annaiah -- Moya, Jesse -- Liu, Haoyuan -- Bell, Daphne W -- Driscoll, David R -- Diederichs, Sven -- Haider, Khaleda -- Netravali, Ilka -- Le, Sheila -- Elia, Roberto -- Dow, Ethan -- Lee, Annette -- Freudenberg, Jan -- De Jager, Philip L -- Chretien, Yves -- Varki, Ajit -- MacDonald, Marcy E -- Gillis, Tammy -- Behrens, Timothy W -- Bloch, Donald -- Collier, Deborah -- Korzenik, Joshua -- Podolsky, Daniel K -- Hafler, David -- Murali, Mandakolathur -- Sands, Bruce -- Stone, John H -- Gregersen, Peter K -- Pillai, Shiv -- AI 064930/AI/NIAID NIH HHS/ -- AI 068759/AI/NIAID NIH HHS/ -- AI 076505/AI/NIAID NIH HHS/ -- AR 022263/AR/NIAMS NIH HHS/ -- AR 044422/AR/NIAMS NIH HHS/ -- AR 058481/AR/NIAMS NIH HHS/ -- NS 32765/NS/NINDS NIH HHS/ -- P30 DK043351/DK/NIDDK NIH HHS/ -- R01 AI064930/AI/NIAID NIH HHS/ -- R01 AI064930-04/AI/NIAID NIH HHS/ -- R01 AI068759/AI/NIAID NIH HHS/ -- R01 AI068759-05/AI/NIAID NIH HHS/ -- R01 AI076505/AI/NIAID NIH HHS/ -- R01 AI076505-02/AI/NIAID NIH HHS/ -- R01 AR044422/AR/NIAMS NIH HHS/ -- R01 AR044422-13/AR/NIAMS NIH HHS/ -- RC1 AR058481/AR/NIAMS NIH HHS/ -- RC1 AR058481-01/AR/NIAMS NIH HHS/ -- England -- Nature. 2010 Jul 8;466(7303):243-7. doi: 10.1038/nature09115. Epub 2010 Jun 16.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20555325" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylation ; Acetylesterase/*genetics/metabolism/secretion ; Alleles ; Animals ; Antibodies, Antinuclear/blood ; Arthritis, Rheumatoid/enzymology/genetics ; Autoimmune Diseases/*enzymology/*genetics ; Autoimmunity/*genetics ; B-Lymphocytes/metabolism ; Biocatalysis ; Carboxylic Ester Hydrolases/*genetics/metabolism/secretion ; Case-Control Studies ; Cell Line ; Diabetes Mellitus, Type 1/enzymology/genetics ; Europe/ethnology ; Exons/genetics ; Genetic Predisposition to Disease/*genetics ; Germ-Line Mutation/*genetics ; Humans ; Mice ; N-Acetylneuraminic Acid/*metabolism ; Odds Ratio ; Polymorphism, Single Nucleotide/genetics ; Sample Size ; Sequence Analysis, DNA
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 3
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    Furfural removal from liquid effluents by adsorption onto commercial activated carbon in a batch heterogeneous reactor (2014)
    Elsevier
    Details
    Publication Date: 2014-07-01
    Print ISSN: 0925-8574
    Electronic ISSN: 1872-6992
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering
    Published by Elsevier
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  • 4
    Electronic Resource
    Electronic Resource
    Morphological factors determining salt tolerance in citrus seedlings: the shoot to root ratio modulates passive root uptake of chloride ions and their accumulation in leaves (1999)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 22 (1999), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The results presented in this work were obtained with two citrus genotypes, the chloride-tolerant Cleopatra mandarin (Citrus reshni Hort. ex Tan.) and the chloride-sensitive Carrizo citrange [Citrus sinensis (L.) Osb. ×Poncirus trifoliata (L.) Raf.]. The data show that chloride uptake under salinization is driven by passive forces. In both species, net rates of chloride root uptake increased linearly, without saturation, with the increase of external NaCl concentrations (30–240 mol m–3). Uptake rates, on a μg g root dry weight–1 h–1 basis, in Cleopatra and Carrizo decreased (from 38 to 21) and increased (from 21 to 35), respectively, with the increase (about three-fold) of the shoot to root ratio. With the appropriate shoot to root ratio in each genotype, it was demonstrated that at identical external doses of NaCl, Cl– uptake rates and Cl– xylem concentrations in the two species were very similar. Root pruning and defoliation showed that the amount of chloride taken by the plant was a function of the size of the root system, whereas leaf chloride concentration, the parameter responsible for salt damage, was dependent upon leaf biomass. Measurements of water transpiration suggested that chloride root uptake and leaf accumulation might be linked to water absorption and transpiration rates, respectively. The data indicate that plant morphology is a crucial factor determining salt-tolerance in citrus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.1999.00495.x
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  • 5
    Electronic Resource
    Electronic Resource
    Physiological and anatomical disturbances induced by chloride salts in sensitive and tolerant citrus: beneficial and detrimental effects of cations (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Plant, cell & environment 21 (1998), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In citrus, the relative contributions of chloride and cations to growth disturbances induced by salinity are a matter of controversy. Chloride salts (15 mol m–3 CaCl2, 30 mol m–3 CaCl and 30 mol m–3 KCl) reduced growth and gas exchange parameters, increased leaf damage and abscission and produced anatomical disarrangements and mineral imbalances in seedlings of sensitive Carrizo citrange (Citrus sinensis x Poncirus trifoliata) and tolerant Cleopatra mandarin (Citrus reshni). In both cultivars, Ca2+ was more beneficial, and K+ more detrimental, for growth than sodium. Photosynthesis and growth disturbances were highly correlated (P≤ 0·001) with leaf Cl– build-up. In the sensitive genotype, Cl– was also significantly correlated with several leaf anatomical disarrangements, such as increase in succulence. In comparison with sodium, both calcium and potassium increased leaf Cl– content (up to 25 and 69%, respectively). Protective calcium effects were not linked to improvement of photosynthesis, reduction of leaf anatomical disarrangements, or prevention of Cl– and Na+ increases. It is proposed that the ameliorative effects of calcium on citrus grown under salinity are mostly related to reduction of leaf abscission. Collectively, the data suggest a cause–effect relationship between Cl– build-up and reduced growth, whereas chloride correlations with declines in photosynthesis or increases in succulence appear to be indirect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.1998.00349.x
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  • 6
    Electronic Resource
    Electronic Resource
    Differentiation of Mediterranean plum pox virus isolates by coat protein analysis (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 43 (1994), S. 0 
    Details
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Six isolates of plum pox potyvirus from different Mediterranean countries were compared by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), peptide mapping and Western blotting after improved purification of virions using a protease inhibitor cocktail that reduced coat protein degradation. One isolate (Spanish isolate 3.3 from plum) differed from the others in possessing a smaller coat protein (approximately 34 instead 36 kDa) with a possible deletion in the surface-exposed amino-terminal region. Infectivity of the viruses after proteolysis, assessed using a local lesion host, was significantly reduced. Protease digestion conditions were established to generate a 28 kDa resistant core of the viral coat protein. Such conditions (longer incubation times or an increase in the enzyme concentration) differed from the milder ones reported for other potyviruses. Implications of the results in relation to the production and screening of virus-specific monoclonal antibodies are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3059.1994.tb00566.x
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  • 7
    Electronic Resource
    Electronic Resource
    CYCLIC FATIGUE OF Al2O3 AND Al2O3-Al2TiO5 COMPOSITES IN DIRECT PUSH-PULL (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 20 (1997), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract— A reaction sintering route is developed to produce, “in situ”, composites of alumina-aluminium titanate using alumina and titania as starting powders. Aluminium titanate, can be formed by a solid state reaction between Al2O3 and TiO2 at temperatures above the eutectoid temperature of 1280°C. These composites have different grain sizes of alumina matrix and a different quantity and distribution of aluminium titanate according to the heating cycle used.In the present work direct push-pull tests under cyclic loads have been carried out with both monolithic alumina and alumina-aluminium titanate composites. It has been found that all the samples show a decrease in tensile strength with the number of applied cycles of loading when plotted in graphical form but the slopes of these graphs for both Al2O3-Al2TiO5 composites are lower than for the alumina specimens. The role of aluminium titanate and the alumina matrix grain size in fatigue crack growth resistance has been studied during push-pull tests, where failure occurs by catastrophic propagation of small surface cracks after a very short regime of subcritical crack growth. These results have been compared with measurements of slow stable fatigue crack growth rates in Al2O3-Al2TiO5 composites carried out elsewhere with pre-notched specimens of the compact tension type. These latter tests provide information about the behaviour of significantly long cracks, i.e. cracks that are several millimetres long.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1997.tb00308.x
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of iron impurities in yttrium-partially stabilized Zirconia
    Amsterdam : Elsevier
    Solid State Ionics 26 (1988), S. 175 
    Details
    ISSN: 0167-2738
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0167-2738(88)90181-6
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  • 9
    Electronic Resource
    Electronic Resource
    Zinc treatment of the digestive gland of the slugArion ater L. 1. Cellular distribution of zinc and calcium (1988)
    Springer
    Bulletin of environmental contamination and toxicology 41 (1988), S. 858-864 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02021047
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  • 10
    Electronic Resource
    Electronic Resource
    Zinc treatment of the digestive gland of the slugArion ater L. 2. Sublethal effects at the histological level (1988)
    Springer
    Bulletin of environmental contamination and toxicology 41 (1988), S. 865-871 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02021048
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