ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Reaction of Bisvinamidinium Salts of 1,1-Dioxo-1,2-thiazine-6-aldehydes with Hydroxylamine to Substituted Pyrido[4,3-e]-1,2-thiazine-1,1-dioxidesBerichtigung der Struktur vom Typ 3 in [2]The formylation of 2-aryl-3,5-dimethyl-1,1-dioxo-1,2-thiazines with POCl3/DMF leads to the thiazine-6-aldehydes 1 and to the bis-vinamidinium salts 2. The reaction of 2a,b with hydroxylamine results in the formation of the pyrido-thiazine-N-oxides 5a,b, which give with PCl3 the 5-cyano-3-isoxazol-4-yl-pyrido[4,3-e]thiazines 6a,b. The pyridothiazines 9a and 10a are obtained by base-induced opening of the isoxazolyl-ring in 5a and 7a to the cyanoformylmethyl group. The compounds 6a and 7a were characterized by X-ray structure analysis.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19963380167
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