Publication Date:
2002-09-07
Description:
The principles that the auditory cortex uses to decipher a stream of acoustic information have remained elusive. Neural responses in the animal auditory cortex can be broadly classified into transient and sustained activity. We examined the existence of similar principles in the human brain. Sound-evoked, blood oxygen level-dependent signal response was decomposed temporally into independent transient and sustained constituents, which predominated in different portions-core and belt-of the auditory cortex. Converging with unit recordings, our data suggest that this spatiotemporal pattern in the auditory cortex may represent a fundamental principle of analyzing sound information.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Seifritz, Erich -- Esposito, Fabrizio -- Hennel, Franciszek -- Mustovic, Henrietta -- Neuhoff, John G -- Bilecen, Deniz -- Tedeschi, Gioacchino -- Scheffler, Klaus -- Di Salle, Francesco -- New York, N.Y. -- Science. 2002 Sep 6;297(5587):1706-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychiatry, University of Basel, 4025 Basel, Switzerland. erich.seifritz@unibas.ch〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12215648" target="_blank"〉PubMed〈/a〉
Keywords:
Acoustic Stimulation
;
Adult
;
Animals
;
Auditory Cortex/cytology/*physiology
;
Auditory Pathways/physiology
;
Auditory Perception/*physiology
;
Brain Mapping
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Neurons/*physiology
;
Oxygen/blood
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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