Publication Date:
2015-07-09
Description:
Article Graves’ disease is the leading cause of hyperthyroidism but treatment options can cause life-threatening complications. Chen et al . conduct two-stage direct HLA genotyping and genome-wide association studies to identify HLA-B *38:02 and HLA-DRB1 *08:03 as major pharmacogenetic determinants. Nature Communications doi: 10.1038/ncomms8633 Authors: Pei-Lung Chen, Shyang-Rong Shih, Pei-Wen Wang, Ying-Chao Lin, Chen-Chung Chu, Jung-Hsin Lin, Szu-Chi Chen, Ching-Chung Chang, Tien-Shang Huang, Keh Sung Tsai, Fen-Yu Tseng, Chih-Yuan Wang, Jin-Ying Lu, Wei-Yih Chiu, Chien-Ching Chang, Yu-Hsuan Chen, Yuan-Tsong Chen, Cathy Shen-Jang Fann, Wei-Shiung Yang, Tien-Chun Chang
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
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Natural Sciences in General
,
Physics
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