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  • 1
    Publication Date: 1979-01-12
    Description: To explore possible mechanisms for the metastasis of malignant cells to bone, a model of tumor cell migration was developed, using Walker carcinosarcoma or malignant lymphoma cells. It was found that bone contains a factor that is strongly chemotactic for tumor cells. This factoor is released by a variety of agents that induce resorption of bone.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Orr, W -- Varani, J -- Gondex, M K -- Ward, P A -- Mundy, G R -- New York, N.Y. -- Science. 1979 Jan 12;203(4376):176-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/569363" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bone Resorption/*physiopathology ; Bone and Bones/*physiopathology ; Carcinoma 256, Walker/*physiopathology ; Cell Line ; Cell Movement ; *Chemotaxis ; Chemotaxis, Leukocyte ; Lymphoma/physiopathology ; Neoplasm Metastasis ; Neoplasms, Experimental/physiopathology ; Organ Culture Techniques
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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